Video: Puas yog poly A tail ib feem ntawm 3 UTR?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Thaum lub sij hawm gene qhia, ib qho mRNA molecule yog transcribed los ntawm DNA ib theem zuj zus thiab tom qab ntawd tau muab txhais ua cov protein. Tsis tas li ntawd, lub 3 '- UTR muaj cov kab ke AAUAAA uas qhia ntxiv ntawm ntau pua adenine residues hu ua poly (A) tail mus rau qhov kawg ntawm mRNA cov ntawv sau tseg.
Hauv qhov no, txhais li cas los ntawm 5 UTR thiab 3 UTR?
Biology Glossary nrhiav los ntawm EverythingBio.com. UA: Thaj tsam tsis tau txhais . 5 ' UTR yog ib feem ntawm mRNA los ntawm lub 5 ' xaus rau txoj haujlwm ntawm thawj codon siv hauv kev txhais lus. Cov 3 ' UTR yog ib feem ntawm mRNA los ntawm lub 3 ' kawg ntawm mRNA mus rau txoj hauj lwm ntawm lub xeem codon siv hauv kev txhais lus.
Qhov thib ob, qhov zoo ntawm poly A Tail yog dab tsi? Cov poly (A) tail tiv thaiv mRNA los ntawm degradation, pab nyob rau hauv lub export ntawm mRNA paub tab mus rau lub cytoplasm, thiab koom nyob rau hauv binding proteins koom tes nyob rau hauv pib txhais lus. Introns raug tshem tawm los ntawm pre-mRNA ua ntej mRNA raug xa tawm mus rau cytoplasm.
Ib yam li ntawd, tib neeg nug, puas yog poly A tail txhais?
Muaj nuj nqi. Hauv nuclear polyadenylation , a poly (A) tail ntxiv rau RNA thaum kawg ntawm kev sau ntawv. Hauv mRNAs, lub poly (A) tail tiv thaiv mRNA molecule los ntawm enzymatic degradation nyob rau hauv lub cytoplasm thiab pab nyob rau hauv transcription termination, export ntawm mRNA los ntawm lub nucleus, thiab txhais lus.
Lub luag haujlwm ntawm 5 UTR yog dab tsi?
Lub cheeb tsam 5' untranslated (5' UTR) (tseem hu ua tus thawj coj ua ntu lossis tus thawj coj RNA) yog thaj tsam ntawm ib qho mRNA uas yog ncaj qha upstream los ntawm pib codon. Lub cheeb tsam no yog qhov tseem ceeb rau kev tswj hwm kev txhais cov ntawv sau los ntawm cov txheej txheem sib txawv hauv cov kab mob, prokaryotes thiab eukaryotes.
Pom zoo:
Yuav ua li cas koj sau ib feem raws li ib tug khoom ntawm ib tug tag nrho cov zauv thiab ib feem feem?
Cov cai los nrhiav cov khoom ntawm ib feem feem thiab tag nrho tus lej Peb xub sau tag nrho cov lej ua ib feem, piv txwv li, sau nws faib los ntawm ib qho; Piv txwv li: 7 yog sau ua 71. Peb mam li muab cov zauv. Peb muab cov denominators. Yog tias yuav tsum tau ua kom yooj yim, nws ua tiav thiab tom qab ntawd peb sau cov feem kawg
Lub luag haujlwm ntawm poly A Tail yog dab tsi?
Muaj nuj nqi. Hauv nuclear polyadenylation, poly(A) tus Tsov tus tw yog ntxiv rau RNA thaum kawg ntawm kev sau ntawv. Ntawm mRNAs, poly(A) tus Tsov tus tw tiv thaiv mRNA molecule los ntawm enzymatic degradation nyob rau hauv lub cytoplasm thiab pab nyob rau hauv transcription termination, export ntawm mRNA los ntawm lub nucleus, thiab kev txhais lus
Muaj pes tsawg tus poly A Tail?
Lub poly(A) tails yog 43 nucleotides ntev ntawm qhov nruab nrab. Cov stabilizing pib ntawm qhov nres codon, thiab tsis muaj lawv qhov nres codon (UAA) tsis tiav raws li cov genome tsuas yog encodes U lossis UA
Poly A Tail tiv thaiv degradation li cas?
Lub poly-A tail ua rau RNA molecule ruaj khov thiab tiv thaiv nws cov degradation. Tsis tas li ntawd, poly-A tus Tsov tus tw tso cai rau tus tub txib paub tab RNA molecule raug xa tawm los ntawm lub hauv paus thiab muab txhais ua cov protein los ntawm ribosomes hauv cytoplasm
Lub luag haujlwm ntawm 5 cap thiab poly A Tail yog dab tsi?
Lub 5 'cap tiv thaiv lub nascent mRNA los ntawm degradation thiab pab nyob rau hauv ribosome khi thaum lub sij hawm txhais lus. Lub poly (A) tus Tsov tus tw tiv thaiv mRNA los ntawm degradation, pab nyob rau hauv lub export ntawm mRNA paub tab mus rau lub cytoplasm, thiab koom nyob rau hauv binding proteins koom nyob rau hauv pib txhais lus