Puas yog poly A tail ib feem ntawm 3 UTR?

2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36

Thaum lub sij hawm gene qhia, ib qho mRNA molecule yog transcribed los ntawm DNA ib theem zuj zus thiab tom qab ntawd tau muab txhais ua cov protein. Tsis tas li ntawd, lub 3 '- UTR muaj cov kab ke AAUAAA uas qhia ntxiv ntawm ntau pua adenine residues hu ua poly (A) tail mus rau qhov kawg ntawm mRNA cov ntawv sau tseg.

Hauv qhov no, txhais li cas los ntawm 5 UTR thiab 3 UTR?

Biology Glossary nrhiav los ntawm EverythingBio.com. UA: Thaj tsam tsis tau txhais . 5 ' UTR yog ib feem ntawm mRNA los ntawm lub 5 ' xaus rau txoj haujlwm ntawm thawj codon siv hauv kev txhais lus. Cov 3 ' UTR yog ib feem ntawm mRNA los ntawm lub 3 ' kawg ntawm mRNA mus rau txoj hauj lwm ntawm lub xeem codon siv hauv kev txhais lus.

Qhov thib ob, qhov zoo ntawm poly A Tail yog dab tsi? Cov poly (A) tail tiv thaiv mRNA los ntawm degradation, pab nyob rau hauv lub export ntawm mRNA paub tab mus rau lub cytoplasm, thiab koom nyob rau hauv binding proteins koom tes nyob rau hauv pib txhais lus. Introns raug tshem tawm los ntawm pre-mRNA ua ntej mRNA raug xa tawm mus rau cytoplasm.

Ib yam li ntawd, tib neeg nug, puas yog poly A tail txhais?

Muaj nuj nqi. Hauv nuclear polyadenylation , a poly (A) tail ntxiv rau RNA thaum kawg ntawm kev sau ntawv. Hauv mRNAs, lub poly (A) tail tiv thaiv mRNA molecule los ntawm enzymatic degradation nyob rau hauv lub cytoplasm thiab pab nyob rau hauv transcription termination, export ntawm mRNA los ntawm lub nucleus, thiab txhais lus.

Lub luag haujlwm ntawm 5 UTR yog dab tsi?

Lub cheeb tsam 5' untranslated (5' UTR) (tseem hu ua tus thawj coj ua ntu lossis tus thawj coj RNA) yog thaj tsam ntawm ib qho mRNA uas yog ncaj qha upstream los ntawm pib codon. Lub cheeb tsam no yog qhov tseem ceeb rau kev tswj hwm kev txhais cov ntawv sau los ntawm cov txheej txheem sib txawv hauv cov kab mob, prokaryotes thiab eukaryotes.