Lub luag haujlwm ntawm 5 cap thiab poly A Tail yog dab tsi?
Lub luag haujlwm ntawm 5 cap thiab poly A Tail yog dab tsi?

Video: Lub luag haujlwm ntawm 5 cap thiab poly A Tail yog dab tsi?

Video: Lub luag haujlwm ntawm 5 cap thiab poly A Tail yog dab tsi?
Video: Xav rov ntsib koj ib zaug dua. 8/8/2018 2024, Kaum ib hlis
Anonim

Cov 5 ' cap tiv thaiv lub nascent mRNA los ntawm degradation thiab pab nyob rau hauv ribosome khi thaum txhais lus. Cov poly (A) tail tiv thaiv mRNA los ntawm degradation, pab nyob rau hauv lub export ntawm mRNA paub tab mus rau lub cytoplasm, thiab koom nyob rau hauv binding proteins koom tes nyob rau hauv pib txhais lus.

Tsis tas li lo lus nug yog, qhov ua haujlwm ntawm poly A Tail yog dab tsi?

Muaj nuj nqi . Hauv nuclear polyadenylation , a poly (A) tail ntxiv rau RNA thaum kawg ntawm kev sau ntawv. Hauv mRNAs, lub poly (A) tail tiv thaiv mRNA molecule los ntawm enzymatic degradation nyob rau hauv lub cytoplasm thiab pab nyob rau hauv transcription termination, export ntawm mRNA los ntawm lub nucleus, thiab kev txhais lus.

Yuav ua li cas yog lub poly A tail ntxiv rau pre mRNA Lub hom phiaj ntawm poly A Tail yog dab tsi? PAP ntxiv kwv yees li 10 adenine nucleotides mus rau qhov kawg ntawm 3' ua ntej - mRNA molecule. Qhov sib ntxiv ntawm luv poly (A) tail tso cai rau kev khi ntawm cov poly (A) binding protein (PABII) to the qab . PABII nce tus nqi ntawm polyadenylation , uas tom qab tso cai rau ntau PABII protein los khi cov qab.

Ib yam li ntawd, tib neeg nug, dab tsi yog lub luag haujlwm ntawm lub hau thiab tus Tsov tus tw ntawm eukaryotic mRNA?

- Lawv koom nrog hauv kev ua kom nrawm ntawm kev txhais lus los ntawm ribosome. - Lawv koom nrog hauv kev tshem tawm exons los ntawm mRNA. - Lawv koom nrog tiv thaiv kev txhais lus ntawm mRNA kom txog thaum nws tawm mus nucleus.

Yuav ua li cas ntxiv poly A Tail?

poly-A tail . Cov poly-A tail yog ib txoj hlua ntev ntawm adenine nucleotides uas yog ntxiv mus rau tus tub txib RNA (mRNA) molecule thaum lub sij hawm RNA ua kom muaj kev ruaj ntseg ntawm cov molecule. Tom qab ntawd ib qho enzyme hu ua poly - Ib qho polymerase ntxiv ib tug saw ntawm adenine nucleotides rau RNA.

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