Muaj pes tsawg tus poly A Tail?

Video: Muaj pes tsawg tus poly A Tail?

2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36

Cov poly (A) tails yog 43 nucleotides ntev nyob nruab nrab. Cov stabilizing pib ntawm qhov nres codon, thiab tsis muaj lawv qhov nres codon (UAA) tsis tiav raws li cov genome tsuas yog encodes U lossis UA.

Hauv qhov no, ntev npaum li cas poly A tail?

Poly (A) tails ntawm mRNAs muaj qhov pib ntev ntawm 70-80 nucleotides nyob rau hauv poov xab thiab ∼250 nucleotides nyob rau hauv mammalian hlwb. Cov no ntev tails muaj kev ua haujlwm ruaj khov: Thoob plaws lub neej cytoplasmic ntawm mRNA, lawv maj mam luv los ntawm lawv 3 kawg.

Vim li cas poly A tails txawv qhov ntev? Ntev tswj tau rov tsim dua nrog premade poly (A) tails ntawm txawv qhov ntev thiab yog insensitive rau loj hloov nyob rau hauv tus nqi elongation. Yog li, tus tswj mechanism tiag ntsuas lub ntev ntawm poly (A) tail . Lub stimulatory action ntawm PAB II zoo ib yam li ntev thiab luv qab.

Ib tug kuj nug, dab tsi yog qhov zoo ntawm poly A tail?

Cov poly (A) tail tiv thaiv mRNA los ntawm degradation, pab nyob rau hauv lub export ntawm mRNA paub tab mus rau lub cytoplasm, thiab koom nyob rau hauv binding proteins koom tes nyob rau hauv pib txhais lus. Introns raug tshem tawm los ntawm pre-mRNA ua ntej mRNA raug xa tawm mus rau cytoplasm.

Cov kab mob RNA puas muaj poly A tail?

Polyadenylation yog postranscriptional hloov kho ntawm RNA pom nyob rau hauv tag nrho cov cell thiab nyob rau hauv organelles. Hauv kab mob , ib feem me me ntawm RNA chaw nres nkoj oligo (A) qab uas feem ntau luv dua 20 As.

Pom zoo:

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Muaj pes tsawg tus koob Virginia Pine muaj?

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