Video: Lub luag haujlwm ntawm poly A Tail yog dab tsi?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Muaj nuj nqi . Hauv nuclear polyadenylation , a poly (A) tail ntxiv rau RNA thaum kawg ntawm kev sau ntawv. Hauv mRNAs, lub poly (A) tail tiv thaiv mRNA molecule los ntawm enzymatic degradation nyob rau hauv lub cytoplasm thiab pab nyob rau hauv transcription termination, export ntawm mRNA los ntawm lub nucleus, thiab kev txhais lus.
Tom qab ntawd, ib tug kuj yuav nug, yuav ua li cas yog lub poly A tail ntxiv rau pre mRNA Lub hom phiaj ntawm poly A Tail yog dab tsi?
PAP ntxiv kwv yees li 10 adenine nucleotides mus rau qhov kawg ntawm 3' ua ntej - mRNA molecule. Qhov sib ntxiv ntawm luv poly (A) tail tso cai rau kev khi ntawm cov poly (A) binding protein (PABII) to the qab . PABII nce tus nqi ntawm polyadenylation , uas tom qab tso cai rau ntau PABII protein los khi cov qab.
Tsis tas li ntawd, muaj pes tsawg tus poly A tail? Poly(A) tails ntawm mRNAs muaj qhov pib ntev ntawm 70-80 nucleotides hauv cov poov xab thiab ∼ 250 nucleotides nyob rau hauv mammalian hlwb. Cov tails ntev no muaj qhov ua haujlwm ruaj khov: Thoob plaws hauv lub neej cytoplasmic ntawm mRNA, lawv maj mam luv los ntawm lawv 3 kawg.
Ib tug kuj yuav nug, poly A tail ntxiv li cas?
poly-A tail . Cov poly-A tail yog ib txoj hlua ntev ntawm adenine nucleotides uas yog ntxiv mus rau tus tub txib RNA (mRNA) molecule thaum lub sij hawm RNA ua kom muaj kev ruaj ntseg ntawm cov molecule. Tom qab ntawd ib qho enzyme hu ua poly - Ib qho polymerase ntxiv ib tug saw ntawm adenine nucleotides rau RNA.
Cov kab mob RNA puas muaj poly A tail?
Polyadenylation yog postranscriptional hloov kho ntawm RNA pom nyob rau hauv tag nrho cov cell thiab nyob rau hauv organelles. Hauv kab mob , ib feem me me ntawm RNA chaw nres nkoj oligo (A) qab uas feem ntau luv dua 20 As.
Pom zoo:
Lub luag haujlwm ntawm CDK yog dab tsi hauv lub cev ua haujlwm ntawm tes tshwj xeeb hauv lub voj voog ntawm tes?
Los ntawm phosphorylation, Cdks teeb liab lub xov tooj ntawm tes uas nws tau npaj kom dhau mus rau theem tom ntej ntawm lub voj voog ntawm tes. Raws li lawv lub npe qhia, Cyclin-Dependent Protein Kinases yog nyob ntawm cyclins, lwm chav kawm ntawm kev tswj hwm cov protein. Cyclins khi rau Cdks, ua kom cov Cdks rau phosphorylate lwm cov molecules
Dab tsi yog qhov txawv ntawm Marine West Coast huab cua thiab dab tsi yog lub luag haujlwm rau cov yam ntxwv ntawd?
Cov ntsiab lus ntawm Marine West Coast Qhov kev nyab xeeb ntawm cov yam ntxwv tseem ceeb yog lub caij ntuj sov me me thiab lub caij ntuj no thiab cov nag lossis daus txhua xyoo. Qhov ecosystem no muaj kev cuam tshuam loj heev los ntawm nws qhov ze rau ntawm ntug dej hiav txwv thiab roob. Nws yog qee zaum hu ua huab cua sab hnub poob ntug dej hiav txwv lossis dej hiav txwv huab cua
Lub organelle twg yog lub luag haujlwm rau lub zog tshuaj uas xav tau rau lub cell ua haujlwm?
Mitochondria Function Mitochondria feem ntau hu ua "powerhouses" lossis "zog factories" ntawm lub xovtooj vim tias lawv yog lub luag haujlwm rau kev ua adenosine triphosphate (ATP), lub xovtooj ntawm lub zog nqa lub cev
Cov txheej txheem dab tsi yog lub luag haujlwm rau txoj haujlwm ua haujlwm sib txawv?
Position-effect variegation (PEV) tshwm sim thaum cov noob ib txwm nyob hauv euchromatin yog sib xyaw nrog heterochromatin los ntawm kev hloov kho lossis hloov pauv. Thaum lub ntim ntim heterochromatin kis thoob plaws heterochromatin / euchromatin ciam teb, nws ua rau kev hloov pauv ntawm kev ntsiag to hauv tus qauv stochastic
Lub luag haujlwm ntawm 5 cap thiab poly A Tail yog dab tsi?
Lub 5 'cap tiv thaiv lub nascent mRNA los ntawm degradation thiab pab nyob rau hauv ribosome khi thaum lub sij hawm txhais lus. Lub poly (A) tus Tsov tus tw tiv thaiv mRNA los ntawm degradation, pab nyob rau hauv lub export ntawm mRNA paub tab mus rau lub cytoplasm, thiab koom nyob rau hauv binding proteins koom nyob rau hauv pib txhais lus