Kev hloov pauv covalent cuam tshuam li cas rau kev ua enzyme?

2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36

Cov covalent txuas ntawm lwm molecule tuaj yeem hloov kho tus kev ua si ntawm cov enzymes thiab ntau lwm cov proteins. Hauv cov xwm txheej no, tus neeg pub khoom molecule muab qhov ua haujlwm moiety uas hloov kho cov khoom ntawm enzyme . Phosphorylation thiab dephosphorylation yog feem ntau tab sis tsis yog tib txoj kev ntawm covalent hloov kho.

Kuj paub yog, kev hloov kho covalent yog dab tsi?

Covalent hloov kho yog enzyme-catalysed alterations ntawm synthesized proteins thiab muaj xws li ntxiv los yog tshem tawm cov tshuaj pab pawg. Kev hloov kho tuaj yeem tsom ib hom amino acid lossis ntau cov amino acids thiab yuav hloov cov tshuaj lom neeg ntawm qhov chaw.

Tsis tas li ntawd, kev hloov pauv enzyme yog dab tsi? Kev hloov kho enzyme : alteration ntawm enzyme cov qauv thiab yog li ntawd, nws txoj haujlwm thiab nws cov haujlwm catalytic los tsim cov metabolites tshiab kom tso cai rau txoj hauv kev tshiab ntawm cov tshuaj tiv thaiv.

Tom qab ntawd, kev hloov pauv covalent puas rov qab tau?

Tus neeg txais khoom feem ntau yog serine, threonine, lossis tyrosine residue, amino acids uas muaj hydroxide. Cov txheej txheem ntawm covalent hloov kho tej zaum thim rov qab , tab sis tsis yog nyob rau hauv txhua rooj plaub. Ib qho piv txwv ntawm covalent Kev tswj hwm yog protein phosphorylation.

Puas yog acetylation yog kev hloov kho covalent?

N-terminal acetylation yog ib qho ntawm kev sib koom ua ke ntau tshaj plaws covalent kev hloov kho ntawm cov proteins hauv eukaryotes, thiab nws yog qhov tseem ceeb rau kev tswj hwm thiab kev ua haujlwm ntawm cov protein sib txawv. N-terminal acetylation plays lub luag haujlwm tseem ceeb hauv kev sib txuas, kev ruaj ntseg thiab hauv zos ntawm cov proteins.