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Cov tshuaj tua kab mob dab tsi inhibits protein synthesis?
Cov tshuaj tua kab mob dab tsi inhibits protein synthesis?

Video: Cov tshuaj tua kab mob dab tsi inhibits protein synthesis?

Video: Cov tshuaj tua kab mob dab tsi inhibits protein synthesis?
Video: Tshuaj Zoo Muaj Zog (Lao EVO) Dietary Supplement Product -Part 2 2024, Kaum ib hlis
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Cov tshuaj tua kab mob tuaj yeem cuam tshuam cov protein synthesis los ntawm kev tsom mus rau 30S subunit, piv txwv xws li spectinomycin, tetracycline, thiab aminoglycosides kanamycin thiab streptomycin, lossis mus rau 50S subunit, piv txwv xws li clindamycin, chloramphenicol linezolid, thiab macrolides erythromycin, Ua qhov no hauv kev xav, dab tsi inhibits protein synthesis?

Cov chav kawm tom ntej ntawm protein synthesis inhibitors yog aminoglycosides. Cov macrolides, xws li erythromycin, yog xav txog inhibit protein synthesis los ntawm kev khi rau 50S subunit thiab thaiv lub qhov uas cov hlua polypeptide yuav tsum tawm mus. Qhov no txhaws cov ribosome thiab nres kev txhais lus.

Ib yam li ntawd, dab tsi yog tshuaj tua kab mob inhibiting protein synthesis tham? Inhibition ntawm Protein Synthesis los ntawm Tshuaj tua kab mob . Lawv muaj peev xwm inhibiting protein synthesis nyob rau hauv ob qho tib si 70S thiab 80S (eukaryotic) ribosomes, tab sis lawv nyiam khi rau cov kab mob ribosomes vim qhov txawv ntawm cov qauv hauv RNA subunits.

Ib yam li ntawd, nws tau nug, cov tshuaj tua kab mob twg muaj feem cuam tshuam rau cov protein synthesis?

Cov tshuaj tua kab mob hauv qab no khi rau 30S subunit ntawm ribosome yog li inhibiting protein synthesis:

  • Aminoglycoside tshuaj tua kab mob xws li:
  • Neomycin sulfate.
  • Amikacin.
  • Gentamicin.
  • Kanamycin sulfate.
  • Spectinomycin.
  • Streptomycin.
  • Tobramycin.

Cov tshuaj tua kab mob dab tsi inhibit DNA synthesis?

Cov tshuaj hauv tsev neeg no, xws li nalidixic acid, ciprofloxacin ua , thiab norfloxacin , ua hauj lwm los ntawm inhibiting enzymes uas yuav tsum tau rau cov kab mob DNA synthesis. Yog li ntawd, nyob rau hauv sib piv rau lub rifamycin tshuaj , uas inhibit transcription ntawm DNA rau hauv RNA, lub quinolones thiab fluoroquinolones inhibit DNA replication.

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