Cov txheej txheem:
Video: Cov tshuaj twg ua los ntawm inhibiting protein synthesis ntawm cov kab mob?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Chloramphenicol . Chloramphenicol yog ib tug dav spectrum tshuaj tua kab mob uas ua raws li ib tug muaj zog inhibitor ntawm cov kab mob protein biosynthesis. Nws muaj keeb kwm kev kho mob ntev ntev tab sis cov kab mob tsis zoo yog tshwm sim.
Tom qab ntawd, cov kab mob twg ua los ntawm inhibiting protein synthesis?
Anisomycin (qee zaum hu ua flagecidin), yog ib qho tshuaj tua kab mob uas tau muab los ntawm cov kab mob Streptomyces griseolus. Cov tshuaj no ua rau inhibit cov kab mob protein thiab DNA synthesis . Puromycin yog tshuaj tua kab mob uas tiv thaiv kab mob protein txhais lus.
Tsis tas li ntawd, cov protein synthesis inhibitors feem ntau siv rau dab tsi? Ob leeg yog protein synthesis inhibitors ua haujlwm ntawm 50S ribosomal subunit. Qhov kev sib xyaw no yog siv tshwj xeeb yog kho cov kab mob Gram zoo resistant xws li vancomycin resistant enterococci (tsuas yog E. faecium) thiab nyuaj methicillin resistant S. aureus (MRSA) kab mob uas vancomycin tsis tuaj yeem. siv.
Tsis tas li ntawd, cov tshuaj twg hauv qab no inhibits protein synthesis?
Cov tshuaj tua kab mob hauv qab no khi rau 30S subunit ntawm ribosome yog li inhibiting protein synthesis:
- Aminoglycoside tshuaj tua kab mob xws li:
- Neomycin sulfate.
- Amikacin.
- Gentamicin.
- Kanamycin sulfate.
- Spectinomycin.
- Streptomycin.
- Tobramycin.
Dab tsi yog cov xwm txheej uas yuav txwv tsis pub cov synthesis ntawm cov protein tshwj xeeb?
Kev txiav txim ntawm protein synthesis tshwm sim ntawm a tshwj xeeb teeb liab hauv mRNA. Cov txheej txheem polypeptide saw polymerization tso tseg thaum lub ribosome ncav cuag ib ntawm peb nres kos npe (codons) ntawm mRNA. The codons are UAA, UAG, and UGA.
Pom zoo:
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Dab tsi yog cov tshuaj tua kab mob cuam tshuam nrog cov protein synthesis?
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