Cov tshuaj tua kab mob twg thaiv cov kab mob protein ntau?
Cov tshuaj tua kab mob twg thaiv cov kab mob protein ntau?

Video: Cov tshuaj tua kab mob twg thaiv cov kab mob protein ntau?

Video: Cov tshuaj tua kab mob twg thaiv cov kab mob protein ntau?
Video: Tshuaj theem vim li cas thiaj tau nqi ?/ Siv kho mob dab tsi?/paris polyphylla use for? 2024, Kaum ib hlis
Anonim

Tetracyclins yog ib hom tshuaj tshuaj tua kab mob uas suav nrog tus thawj tetracycline nrog rau doxycycline thiab minocycline. Cov no tshuaj tua kab mob khi rau A qhov chaw ntawm 30s ribosome, tiv thaiv tRNA los ntawm kev nqa cov amino acids tshiab. Yog tias tRNA tsis tuaj yeem txuas rau ribosome, ces tsis muaj qhov tshiab cov proteins tuaj yeem ua tau.

Yog li ntawd, cov tshuaj tua kab mob twg inhibit protein synthesis?

Cov tshuaj tua kab mob tuaj yeem tiv thaiv kev sib txuas ntawm cov protein los ntawm kev tsom mus rau 30S subunit, piv txwv xws li spectinomycin, tetracycline, thiab aminoglycosides kanamycin thiab streptomycin, lossis rau 50S subunit, piv txwv xws li clindamycin, chloramphenicol linezolid, thiab macrolides erythromycin, Tsis tas li ntawd, cov tshuaj tua kab mob twg tsis cuam tshuam kev txhais cov kab mob? Lincomycin thiab clindamycin yog cov inhibitors tshwj xeeb ntawm peptidyl transferase, thaum macrolides tsis ncaj qha inhibit enzyme.

Ntawm no, cov tshuaj tua kab mob uas inhibit protein synthesis ua haujlwm li cas?

Tag nrho cov tshuaj tua kab mob lub hom phiaj kab mob protein synthesis ua yog li los ntawm kev cuam tshuam nrog cov kab mob ribosome thiab inhibiting nws txoj haujlwm. Lub ribosome yuav tsis zoo li lub hom phiaj zoo rau kev xaiv toxicity, vim hais tias txhua lub hlwb, nrog rau peb tus kheej, siv ribosomes rau protein synthesis.

Cov tshuaj tua kab mob twg tuaj yeem tiv thaiv kev tsim cov protein los ntawm kev tiv thaiv kab mob ribosomes los ntawm kev ua haujlwm?

Tetracyclines thiab Tigecycline (ib qho glycylcycline ntsig txog rau tetracyclines) thaiv lub site A ntawm lub ribosome , tiv thaiv Kev sib txuas ntawm aminoacyl tRNAs.

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