Dab tsi yog cov tshuaj tua kab mob cuam tshuam nrog cov protein synthesis?
Dab tsi yog cov tshuaj tua kab mob cuam tshuam nrog cov protein synthesis?

Video: Dab tsi yog cov tshuaj tua kab mob cuam tshuam nrog cov protein synthesis?

Video: Dab tsi yog cov tshuaj tua kab mob cuam tshuam nrog cov protein synthesis?
Video: Tshuaj theem vim li cas thiaj tau nqi ?/ Siv kho mob dab tsi?/paris polyphylla use for? 2024, Kaum ib hlis
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Erythromycin, macrolide, khi rau 23S rRNA tivthaiv ntawm 50S ribosome thiab cuam tshuam nrog kev sib dhos ntawm 50S subunits. Erythromycin, roxithromycin, thiab clarithromycin tag nrho tiv thaiv elongation ntawm cov kauj ruam transpeptidation ntawm synthesis los ntawm kev thaiv cov 50S polypeptide export qhov.

Tib neeg kuj nug, ua li cas cov tshuaj tua kab mob cuam tshuam rau protein synthesis?

Tag nrho cov tshuaj tua kab mob lub hom phiaj kab mob protein synthesis ua yog li los ntawm kev cuam tshuam nrog cov kab mob ribosome thiab inhibiting nws txoj haujlwm. Lub ribosome yuav tsis zoo li lub hom phiaj zoo rau kev xaiv toxicity, vim hais tias txhua lub hlwb, nrog rau peb tus kheej, siv ribosomes rau protein synthesis.

Ib yam li ntawd, cycloheximide inhibits protein synthesis li cas? Cycloheximide yog ib tug tshwm sim fungicide tsim los ntawm cov kab mob Streptomyces griseus. Cycloheximide exerts nws cov teebmeem los ntawm kev cuam tshuam nrog lub translocation kauj ruam nyob rau hauv protein synthesis (kev txav ntawm ob lub tRNA molecules thiab mRNA nyob rau hauv kev sib raug zoo rau ribosome), yog li thaiv eukaryotic translational elongation.

Ib yam li ntawd, dab tsi txwv cov protein synthesis?

Kev txiav txim ntawm protein synthesis tshwm sim ntawm ib qho teeb meem tshwj xeeb hauv mRNA. Cov txheej txheem polypeptide saw polymerization tso tseg thaum lub ribosome ncav cuag ib ntawm peb nres kos npe (codons) ntawm mRNA. The codons are UAA, UAG, and UGA.

Cov tshuaj tua kab mob twg tuaj yeem tiv thaiv kev tsim cov protein los ntawm kev tiv thaiv kab mob ribosomes los ntawm kev ua haujlwm?

Tetracyclines thiab Tigecycline (ib qho glycylcycline ntsig txog rau tetracyclines) thaiv lub A site ntawm lub ribosome , tiv thaiv Kev sib txuas ntawm aminoacyl tRNAs.

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