Nucleotide excision kho yog dab tsi?
Nucleotide excision kho yog dab tsi?

Video: Nucleotide excision kho yog dab tsi?

Video: Nucleotide excision kho yog dab tsi?
Video: ca ntuj tsis pab tu neeg siab zoo ; nkauj noog hawj ; nkauj tawm tshiab 2022 2024, Kaum ib hlis
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Hauv nucleotide excision kho (NER), cov hauv paus puas raug txiav tawm hauv ib txoj hlua ntawm nucleotides, thiab hloov nrog DNA raws li qhia los ntawm cov qauv tsis raug puas tsuaj. Qhov no kho system yog siv los tshem tawm pyrimidine dimers tsim los ntawm UV hluav taws xob nrog rau nucleotides hloov kho los ntawm cov khoom siv tshuaj lom neeg ntau.

Hais txog qhov no, nucleotide excision kho siv rau dab tsi?

Nucleotide excision kho (NER) yog txoj hauv kev loj siv los ntawm cov tsiaj txhu kom tshem tawm cov kab mob DNA loj xws li cov tsim los ntawm UV teeb, ib puag ncig mutagens, thiab qee cov qog nqaij hlav qog noj ntshav los ntawm DNA.

Tsis tas li ntawd, hom kev hloov pauv DNA uas feem ntau kho los ntawm nucleotide excision kho? Nucleotide excision kho yog thawj kho system rau bulky DNA adducts xws li cyclobutane pyrimidine dimer (PyrPyr), (6–4) photoproduct, benzo[a]pyrene-guanine adduct, acetylaminofluorene-guanine (AAF-G), thiab cisplatin-d (GpG) diadduct.

Ua raws li qhov no, qhov sib txawv ntawm nucleotide excision kho thiab kho lub hauv paus excision yog dab tsi?

Excision kho : Kev puas tsuaj rau ib qho lossis ob peb hauv paus DNA feem ntau kho los ntawm kev tshem tawm ( kev txiav txim ) thiab hloov cov cheeb tsam puas. Hauv puag excision kho , tsuas yog lub puas puag raug tshem tawm. Hauv nucleotide excision kho , as hauv tsis sib haum kho peb pom saum toj no, ib thaj ntawm nucleotides raug tshem tawm.

Photoreactivation kho yog dab tsi?

Photoreactivation yog hom DNA kho Cov txheej txheem muaj nyob rau hauv prokaryotes, archaea thiab ntau eukaryotes. Nws yog qhov rov qab los ntawm ultraviolet irradiated kev puas tsuaj ntawm DNA los ntawm pom lub teeb. Hauv DNA no kho cov txheej txheem hlwb rov qab nws cov DNA tom qab UV raug cuam tshuam rau kev puas tsuaj.

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