Cov txheej txheem:

Lub hauv paus excision kho kho yog dab tsi?
Lub hauv paus excision kho kho yog dab tsi?

Video: Lub hauv paus excision kho kho yog dab tsi?

Video: Lub hauv paus excision kho kho yog dab tsi?
Video: Dab ntxwg nyoos yog leej twg ...zaj no zoo heev. 2024, Kaum ib hlis
Anonim

Cov Base excision kho (BER) yog lub cellular mechanism uas kho puas DNA thoob plaws hauv lub voj voog ntawm tes. Nws yog lub luag haujlwm feem ntau yog tshem tawm me me, tsis yog-helix-distorting puag cov kab mob los ntawm genome. Qhov cuam tshuam nucleotide excision kho txoj kev kho loj helix-distorting lesions.

Kuj paub, yuav ua li cas tshwm sim nrog lub hauv paus excision kho?

Base excision kho Txhua glycosylase ntes thiab tshem tawm ib hom kev puas tsuaj puag . Piv txwv li, cov tshuaj tiv thaiv hu ua deamination tuaj yeem hloov cytosine puag ua uracil,a puag feem ntau pom tsuas yog hauv RNA.

Kuj Paub, koj txhais li cas los ntawm kev kho excision? Xovxwm tshaj tawm. Biology Glossary nrhiav los ntawm EverythingBio.com. Cov txheej txheem uas cov hlwb tshem tawm ib feem ntawm cov DNA puas lawm thiab hloov nws los ntawm DNA synthesis siv cov hlua uas tsis muaj kev puas tsuaj ua tus qauv. Cov kho ntawm DNA lesion los ntawm kev tshem tawm cov faulty DNA ntu thiab nws hloov nrog ib ntu tshiab.

Kuj paub, dab tsi yog cov kauj ruam hauv kev kho qhov kev txiav txim siab?

Base Excision Kho Txoj Kev

  • Proteins koom nrog hauv kev kho cov txheej txheem. DNA glycosylases: DNA glycosylases tig lub hauv paus puas tawm ntawm ob lub helix, thiab tshem tawm N-glycosidic daim ntawv cog lus ntawm lub hauv paus puas, tawm hauv AP site.
  • long-patch thiab luv-patch kho.

Dab tsi yog nucleotide excision kho siv rau?

Nucleotide excision kho (NER) yog txoj hauv kev loj siv los ntawm cov tsiaj txhu kom tshem tawm cov kab mob DNA loj xws li cov tsim los ntawm UV teeb, ib puag ncig mutagens, thiab qee cov qog nqaij hlav qog noj ntshav los ntawm DNA.

Pom zoo: