Puas yog frameshift mutations muaj teeb meem?
Puas yog frameshift mutations muaj teeb meem?

Video: Puas yog frameshift mutations muaj teeb meem?

Video: Puas yog frameshift mutations muaj teeb meem?
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Anonim

Frameshift kev hloov pauv yog kev ntxig lossis tshem tawm ntawm nucleotides hauv DNA uas hloov cov kab ntawv nyeem (cov pab pawg ntawm codons) thiab tsim kev ua yuam kev thaum lub sijhawm DNA synthesis. Kev phom sij ntawm ib qho twg kev hloov pauv feem ntau muaj xws li: Ib qho txawv txav DNA sib lawv liag (mRNA) Ua rau cov protein hloov pauv txawv txav.

Ib sab ntawm qhov no, puas yog kev hloov pauv hloov tsis zoo?

Ntxig lossis tshem tawm ua rau a ncej-hloov uas hloov cov kev nyeem ntawv tom ntej codons thiab, yog li ntawd, hloov tag nrho cov amino acid ib ntus uas ua raws li cov kev hloov pauv , insertions thiab deletions feem ntau yog ntau dua phom sij dua li kev hloov pauv uas tsuas yog ib qho amino acid hloov pauv.

Tsis tas li ntawd, ob hom kev hloov pauv hloov pauv yog dab tsi? muaj ob hom kev hloov pauv hloov pauv . Lawv yog insertions thiab deletes. Insertions koom nrog kev tso ib qho ntawm cov nucleotides ntxiv rau hauv cov saw DNA.

Hais txog qhov no, qhov kev hloov pauv hloov pauv ua li cas?

A frameshift kev hloov yog caj ces kev hloov pauv tshwm sim los ntawm kev tshem tawm lossis tso rau hauv DNA ib ntus uas hloov txoj hauv kev nyeem ntawv. Yog li ntawd, frameshift mutations ua rau Cov khoom lag luam tsis txawv txav nrog cov amino acid tsis raug raws li qhov ntawd ua tau yuav ntev los yog luv dua li cov protein ib txwm.

Qhov kev hloov pauv twg yog qhov teeb meem tsawg tshaj plaws?

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