Dab tsi yog qhov ua haujlwm ntawm enzyme topoisomerase hauv DNA replication?
Dab tsi yog qhov ua haujlwm ntawm enzyme topoisomerase hauv DNA replication?

Video: Dab tsi yog qhov ua haujlwm ntawm enzyme topoisomerase hauv DNA replication?

Video: Dab tsi yog qhov ua haujlwm ntawm enzyme topoisomerase hauv DNA replication?
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Topoisomerases yog cov enzymes uas koom nyob rau hauv lub overwinding los yog underwinding ntawm DNA . Qhov teeb meem winding ntawm DNA tshwm sim vim qhov intertwined xwm ntawm nws ob-helical qauv. Thaum DNA replication thiab transcription, DNA ua overwound ua ntej ntawm ib rov ua dua diav rawg.

Tsis tas li ntawd, qhov ua haujlwm ntawm enzyme topoisomerase hauv DNA replication quizlet yog dab tsi?

cais cov strands los ntawm kev paub txog keeb kwm, rhuav tshem hydrogen bonds, thiab ua a rov ua dua npuas. Dab tsi yog qhov Lub hom phiaj ntawm topoisomerase ? unwinds lub resulting supercoils.

Ib tug kuj yuav nug, dab tsi enzymes koom nrog DNA replication? Enzymes koom nrog hauv DNA replication yog:

  • Helicase (Unwinds DNA ob helix)
  • Gyrase (relieves lub buildup ntawm torque thaum unwinding)
  • Primase (ntev RNA primers)
  • DNA polymerase III (lub ntsiab DNA synthesis enzyme)
  • DNA polymerase I (hloov RNA primers nrog DNA)
  • Ligase (ua rau hauv qhov khoob)

Hais txog qhov no, lub luag haujlwm ntawm topoisomerase hauv DNA replication yog dab tsi?

Topoisomerase Kuv yog ib tug ubiquitous enzyme uas nws muaj nuj nqi nyob rau hauv vivo yog los txo cov torsional strain nyob rau hauv DNA , tshwj xeeb kom tshem tawm cov supercoils zoo tsim nyob rau hauv pem hauv ntej ntawm lub rov ua dua diav rawg thiab txo qhov tsis zoo supercoils tshwm sim hauv qab ntawm RNA polymerase thaum transcription.

Helicases thiab topoisomerases yog dab tsi?

Zog thiab Metabolism Koj hais yog lawm, helicases thiab topoisomerases yog ob chav sib txawv ntawm cov enzymes. Helicases unwind ob-stranded DNA (ntawm ob peb lwm yam dej num uas peb tsis tau tham txog) thiab nyob rau hauv cov txheej txheem rhuav hydrogen bonds. Topoisomerases ua hauj lwm ntawm ob-stranded DNA kom relive lossis induce supercoils.

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