Video: Yuav ua li cas kho cov noob ib hnub twg los kho cov kab mob caj ces?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Kev kho noob caj noob ces , ib txoj kev sim, siv noob hauv kev tiv thaiv thiab kho ntau yam kab mob . Cov kws tshawb fawb kho mob tau sim ntau txoj hauv kev uas gene kho tau ua siv los kho cov kab mob caj ces . Cov kws kho mob cia siab rau kho cov neeg mob los ntawm kev ntxig a noob ncaj qha mus rau hauv ib lub xovtooj ntawm tes, hloov qhov kev xav tau ntawm cov tshuaj lossis kev phais.
Yog li, kev kho noob caj noob ces tuaj yeem kho cov kab mob caj ces?
Kev kho noob caj noob ces hloov qhov yuam kev noob los yog ntxiv ib qho tshiab noob nyob rau hauv ib qho kev sim kho kab mob los yog txhim kho koj lub cev muaj peev xwm tiv thaiv kab mob. Kev kho noob caj noob ces tuav cov lus cog tseg rau kev kho ntau yam kab mob , xws li mob qog noj ntshav, cystic fibrosis, kab mob plawv, ntshav qab zib, hemophilia thiab AIDS.
Ib yam li ntawd, cov kab mob dab tsi tau kho tau? 7 Kab Mob CRISPR Technology tuaj yeem kho tau
- Mob qog noj ntshav. Thawj daim ntawv thov ntawm CRISPR tuaj yeem ua rau mob qog noj ntshav.
- Ntshav tsis txaus.
- Qhov muag tsis pom kev.
- AIDS.
- Cystic fibrosis.
- Muscular dystrophy.
- Huntington tus kab mob.
Ib yam li ntawd, tib neeg nug, yuav siv cov tshuaj kho noob li cas los daws cov teeb meem cuam tshuam nrog cov kab mob caj ces?
Gene therapy yog ib txoj kev sim uas siv noob kho lossis tiv thaiv kab mob. Yav tom ntej, cov txheej txheem no muaj cia cov kws kho mob kho a tsis meej pem los ntawm inserting a noob mus rau hauv tus neeg mob lub hlwb es tsis txhob siv tshuaj los yog phais. Hloov ib tug mutated noob uas ua rau muaj kab mob nrog daim ntawv noj qab haus huv ntawm tus noob.
Kev kho cov noob caj noob ces zoo li cas?
Kev kho noob caj noob ces yog tsim los qhia caj ces cov khoom siv rau hauv cov hlwb kom them rau qhov txawv txav noob los yog ua ib muaj txiaj ntsig protein ntau. Yog mutated noob ua rau cov protein tsim nyog ua yuam kev lossis ploj lawm, kev kho noob caj noob ces tej zaum yuav muaj peev xwm qhia tau ib qho kev luam ntawm cov noob kom rov ua haujlwm ntawm cov protein.
Pom zoo:
Dab tsi yog txhais los ntawm cov noob tseem ceeb thiab cov noob caj noob ces?
(Nyob rau hauv cov ntsiab lus ntawm caj ces, ib qho tseem ceeb tshaj plaws yog ib qho uas yog phenotypically qhia hauv heterozygotes). Ib qho tseem ceeb tshaj plaws yog tawm tsam qhov tsis zoo uas tshwm sim tsuas yog thaum muaj ob daim ntawv theej ntawm cov noob. (Nyob rau hauv cov ntsiab lus genetic, ib tug recessive zoo yog ib tug uas yog phenotypically qhia tsuas yog nyob rau hauv homozygotes)
Kev kho cov noob caj noob ces yog dab tsi?
"Traditional" gene therapy muaj peev xwm kov yeej qee yam kab mob caj ces los ntawm kev ntxiv cov ntawv luam ntawm cov noob uas ploj lawm lossis tsis zoo rau tus neeg mob. Hmoov tsis zoo, txoj hauv kev no tsuas yog siv tau rau cov kab mob caj ces thiab tsis tshua muaj kev kho mob tas mus li
Yuav ua li cas tus tsim cov nyhuv ua rau cov noob caj noob ces?
Genetic drift tuaj yeem ua rau poob loj ntawm kev hloov caj ces rau cov neeg me. Qhov tshwm sim tus tsim tshwm sim thaum lub colony tshiab pib los ntawm ob peb tus tswv cuab ntawm thawj cov pej xeem. Cov pej xeem me me no txhais tau hais tias cov cheeb tsam yuav muaj: txo cov noob caj noob ces los ntawm cov neeg qub
Yuav ua li cas cov khoom siv caj ces hauv txhua lub xov tooj tshiab tsim los ntawm kev faib tawm ntawm tes sib piv nrog cov khoom siv caj ces hauv lub xov tooj qub?
Mitosis tshwm sim nyob rau hauv ob lub nuclei uas zoo tib yam rau thawj nucleus. Yog li, ob lub hlwb tshiab tsim tom qab kev faib tawm ntawm tes muaj tib yam khoom siv caj ces. Thaum lub sij hawm mitosis, chromosomes condense los ntawm chromatin. Thaum saib nrog lub microscope, chromosomes pom nyob rau hauv lub nucleus
Ib puag ncig ntawm ib lub xov tooj ntawm tes thiab cov kab mob cuam tshuam li cas ntawm cov noob caj noob ces?
Splicing ntawm mRNA nce tus naj npawb ntawm cov protein sib txawv uas lub cev muaj peev xwm tsim tau. Gene qhia yog tswj los ntawm cov proteins uas khi rau cov hauv paus hauv paus hauv DNA. Ib puag ncig ntawm ib lub xovtooj ntawm tes thiab ntawm lub cev muaj feem cuam tshuam rau cov noob caj noob ces