Puas yog txhua tus kab mob retroviruses siv rov qab transcriptase?
Puas yog txhua tus kab mob retroviruses siv rov qab transcriptase?

Video: Puas yog txhua tus kab mob retroviruses siv rov qab transcriptase?

Video: Puas yog txhua tus kab mob retroviruses siv rov qab transcriptase?
Video: Tus KAB MOB PUAS HLWB muaj feem mob rau txhua tus 2024, Kaum ib hlis
Anonim

Retroviruses siv rov qab transcriptase los hloov lawv ib leeg-stranded RNA mus rau ob-stranded DNA. Nws yog DNA uas khaws cov genome ntawm tib neeg cov hlwb thiab cov hlwb los ntawm lwm cov ntaub ntawv muaj sia nyob. Thaum hloov los ntawm RNA mus rau DNA, tus kab mob DNA tuaj yeem raug muab tso rau hauv genome ntawm cov kab mob.

Raws li txoj cai, cov kab mob retroviruses puas muaj qhov rov qab transcriptase?

Rov qab transcriptase , kuj hu ua RNA-directed DNA polymerase, ib qho enzyme encoded los ntawm cov khoom siv caj ces ntawm retroviruses uas catalyzes kev sau ntawv ntawm retrovirus RNA (ribonucleic acid) rau hauv DNA (deoxyribonucleic acid).

Tom qab ntawd, lo lus nug yog, tus kab mob twg muaj qhov rov qab transcriptase? Rov qab Transscriptase . Reverse transcriptase yog ib qho RNA-dependent DNA polymerase uas tau pom nyob rau hauv ntau retroviruses xws li tib neeg kev tiv thaiv kab mob kab mob vais lav (HIV) thiab avian myeloblastosis kab mob vais lav (AMV) xyoo 1970.

Ua raws li qhov no hauv kev txiav txim siab, puas yog txhua tus kab mob siv rov qab transcriptase?

Replication fidelity Ua ntej ntawm tag nrho , cov rov qab transcriptase synthesizes tus kab mob DNA los ntawm tus kab mob RNA, thiab tom qab ntawd los ntawm cov tshiab ua ntxiv DNA strand. Rov qab transcriptase muaj qhov yuam kev siab thaum hloov RNA rau hauv DNA txij li, tsis zoo li feem ntau Lwm cov DNA polymerases, nws tsis muaj peev xwm ua pov thawj.

Dab tsi siv rov qab transcriptase?

Rov qab transcriptase tsav txoj kev sib txawv hauv cov txheej txheem molecular hauv hlwb, hloov RNA rov qab mus rau DNA. Txawm hais tias nws txawv heev ntawm cov txheej txheem ib txwm muaj, rov qab transcriptase yog ib qho tseem ceeb enzyme. Nws yog tsim nyog rau kev ua haujlwm hauv cov kab mob, eukaryotes thiab prokaryotes.

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