Video: Puas yog spliceosome yog ribozyme?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Cov spliceosome yog ib lub rooj sib txoos loj ntawm 5 RNAs thiab ntau cov proteins uas, ua ke, ua kom cov khoom ua ntej-mRNA (pre-mRNA) splicing. Txawm li cas los xij, lub spliceosome raws li tshuaj ribozyme hypothesis tau nyuaj heev los ua pov thawj, rau 2 qhov laj thawj loj. Ua ntej, lub spliceosome muaj ntau cov proteins uas tseem ceeb rau kev sib txuas (2).
Ua li no, snRNA puas yog ribozyme?
Spliceosomes tshem tawm introns thiab splice lub exons ntawm feem ntau cov noob caj noob ces. Lawv yog tsim los ntawm 5 hom me me nuclear RNA ( snRNA ) molecules thiab tshaj 100 txawv protein molecules. Nws yog RNA - tsis yog cov protein - uas catalyzes cov tshuaj tiv thaiv splicing.
Qhov thib ob, dab tsi ua rau lub spliceosome? Kev sib xyaw. Txhua spliceosome yog tsim los ntawm tsib me me nuclear RNAs (snRNA) thiab ntau yam cuam tshuam nrog cov protein ntau. Thaum cov RNAs me me no ua ke nrog cov protein ntau, lawv ua RNA-protein complexes hu ua snRNPs (me me nuclear ribonucleo proteins, pronounced "snurps").
Qhov thib ob, puas yog spliceosome ib qho enzyme?
Cov spliceosome yog kawg ib enzyme uas ua rau RNA substrate. Nws kuj yog ib qho RNP complex uas tau hloov zuj zus nyob ib puag ncig ntawm tsib lub RNA luv luv uas yog cov xeeb leej xeeb ntxwv ntawm ib qho qub catalytic RNA.
Dab tsi yog ribozyme?
A tshuaj ribozyme yog ib qho ribonucleic acid (RNA) enzyme uas catalyzes cov tshuaj tiv thaiv. Cov tshuaj ribozyme catalyses tshwj xeeb cov tshuaj tiv thaiv zoo ib yam li cov protein enzymes. Kuj hu ua catalytic RNA, cov ribozymes muaj nyob rau hauv lub ribosome uas lawv koom nrog cov amino acids ua ke los tsim cov protein chains.
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