Dr3 thiab dr4 yog dab tsi?
Dr3 thiab dr4 yog dab tsi?

Video: Dr3 thiab dr4 yog dab tsi?

Video: Dr3 thiab dr4 yog dab tsi?
Video: Qhia txog txoj hauv kev yuav computer los ua 3D animation 2024, Kaum ib hlis
Anonim

DR 3 yog ib feem ntawm noob-allele ntawm AH8. 1 haplotype hauv Northern thiab Western Europeans. Genes ntawm B8 thiab DR 3 ntawm no haplotype feem ntau txuam nrog autoimmune kab mob. Hom 1 mob ntshav qab zib mellitus muaj feem cuam tshuam nrog HLA- DR 3 lub HLA- DR 4.

Kuj tseem paub yog, dr4 yog dab tsi?

DR 4 . Ib qho protein nyob rau saum npoo ntawm qee lub hlwb uas khi lwm cov protein hu ua TRAIL, uas tuaj yeem tua qee cov qog nqaij hlav cancer. Kev nce ntawm tus nqi lossis kev ua haujlwm ntawm DR 4 ntawm cov qog nqaij hlav cancer yuav tua ntau lub hlwb.

Tsis tas li ntawd, HLA DR sawv cev rau dab tsi? HLA - DR yog MHC Class II cell nto receptor encoded los ntawm tib neeg leukocyte antigen complex ntawm chromosome 6 cheeb tsam 6p21. 31. Lub complex ntawm HLA - DR (Tib neeg Leukocyte Antigen - DR isotype) thiab peptide, feem ntau ntawm 9 thiab 30 amino acids nyob rau hauv ntev, ua ib ligand rau T-cell receptor (TCR).

Ntawm no, cov hlwb dab tsi qhia HLA DR?

HLA - DR yog ib qho antigen nthuav tawm molecule qhia nyob rau theem siab ntawm kev tshaj lij antigen nthuav tawm hlwb , tab sis nws cov lus qhia ntawm effector T lymphocytes thaum lawv ua kom muaj zog kuj tau piav qhia ntau yam hauv qee cov kab mob, xws li cov kab mob tsis muaj zog tiv thaiv kab mob thiab kis kab mob (14, 15).

Dab tsi yog human leukocyte antigen?

Cov tib neeg leukocyte antigen ( HLA ) system los yog complex yog ib tug gene complex encoding lub loj histocompatibility complex (MHC) proteins nyob rau hauv tib neeg . Cov cell-surface proteins yog lub luag haujlwm rau kev tswj hwm lub cev tiv thaiv kab mob hauv tib neeg . Cov HLA gene complex nyob ntawm 3 Mbp stretch hauv chromosome 6p21.

Pom zoo: