Cov txheej txheem:

Cov kab mob dab tsi cuam tshuam rau Golgi apparatus?
Cov kab mob dab tsi cuam tshuam rau Golgi apparatus?

Video: Cov kab mob dab tsi cuam tshuam rau Golgi apparatus?

Video: Cov kab mob dab tsi cuam tshuam rau Golgi apparatus?
Video: Tshuaj theem vim li cas thiaj tau nqi ?/ Siv kho mob dab tsi?/paris polyphylla use for? 2024, Kaum ib hlis
Anonim

Dysfunction ntawm cov Golgi apparatus txuas rau neurodegenerative kab mob . Disabling ib feem ntawm lub hlwb hlwb uas ua raws li ib tug kais los tswj cov ndlwg ntawm cov proteins tau pom tias yuav ua rau neurodegeneration, ib txoj kev tshawb no tshiab tau pom.

Ib yam li ntawd, nws raug nug, cov kab mob dab tsi cuam tshuam nrog Golgi apparatus?

- Tangier kab mob thiab hom-C Niemann-Pick kab mob ; Cov teeb meem cuam tshuam nrog kev thauj cov lipids hauv GA. autoimmune kab mob thiab cov tshuaj tiv thaiv tiv thaiv GA. - Sjogren's syndrome thiab p230 trans- Golgi protein ntau. - Systemic lupus erythematosus thiab Golgin-95 thiab -160 kD proteins.

Ib yam li ntawd, Golgi apparatus ua rau Alzheimer's li cas? Cov kws tshawb fawb pom tau hais tias kev sib sau ntawm Abeta peptide - thawj qhov ua txhaum ntawm kev tsim cov plaques uas tua cov hlwb hauv Alzheimer tus kab mob hlwb - ua rau Golgi fragmentation los ntawm activating ib enzyme hu ua cdk5 uas hloov Golgi structural proteins xws li GRASP65.

Raws li, yuav ua li cas tshwm sim thaum lub cuab yeej Golgi puas lawm?

Yog vim li cas qhov tsis xws luag , GMAP-210 tsis muaj peev xwm txav tau cov proteins, thiab lawv tseem nyob hauv cov endoplasmic reticulum , uas swells. Qhov poob ntawm Golgi apparatus kev ua haujlwm cuam tshuam rau qee lub hlwb, xws li cov luag haujlwm tsim cov pob txha thiab pob txha mos, ntau dua li lwm tus.

Cov kab mob dab tsi tshwm sim los ntawm organelles?

Cov kab mob cuam tshuam nrog qee cov cell-organelles

  • Cilia thiab Kartagner syndrome. Nws yog ib qho txawv ntawm thawj ciliary dyskinesia uas muaj bronchiectasis, situs inversus, thiab mob sinusitis.
  • Golgi lub cev thiab I-cell kab mob.
  • Lysosomes thiab Pompe Kab Mob.
  • Ribosomes thiab Treacher-Collins syndrome.
  • Mitochondria thiab MELAS syndrome.

Pom zoo: