Video: Lub luag haujlwm ntawm transmembrane proteins yog dab tsi?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Ib qho transmembrane protein (TP) yog ib hom kab mob sib xyaw ua ke ntawm cov protein uas nthuav tawm tag nrho ntawm cov kab mob. cell daim nyias nyias. Ntau cov proteins transmembrane ua haujlwm raws li lub rooj vag tso cai rau thauj ntawm cov khoom tshwj xeeb hla ntawm daim nyias nyias.
Yog li ntawd, dab tsi lub luag hauj lwm ua lub transmembrane protein ua si?
Transmembrane proteins ua si ob peb luag hauj lwm hauv kev ua haujlwm ntawm cov cell. Kev sib txuas lus yog ib qho tseem ceeb tshaj plaws luag hauj lwm : Cov cov proteins muaj txiaj ntsig zoo rau kev taw qhia rau lub xov tooj ntawm qhov chaw sab nraud muaj. Receptors muaj peev xwm ntawm interacting nrog rau tej substrate molecules ntawm lub extracellular domain.
Ib sab saum toj, dab tsi yog piv txwv ntawm transmembrane protein? Piv txwv ntawm qhov kev txiav txim ntawm transmembrane cov protein . Cov neeg thauj khoom nqa ib qho molecule (xws li qabzib) los ntawm ib sab ntawm cov plasma membrane mus rau lwm qhov. Receptors tuaj yeem khi ib qho molecule extracellular (daim duab peb sab), thiab qhov no ua rau cov txheej txheem intracellular.
Hauv qhov no, dab tsi yog cov haujlwm ntawm cov protein ntau?
Muaj nuj nqi [hloov kho] Integral membrane proteins ua hauj lwm raws li transporters, raws (saib Potassium Channel), linkers, receptors, proteins koom nrog hauv tsub zuj zuj zog, thiab proteins lub luag hauj lwm rau cell adhesion. Piv txwv suav nrog cov tshuaj insulin, Integrins, Cadherins, NCAMs, thiab Selectins.
Lub luag haujlwm ntawm glycoproteins yog dab tsi?
Glycoproteins ua ntau yam tseem ceeb muaj nuj nqi hauv cov hlwb; lawv lub ntsiab luag hauj lwm yog kev koom tes hauv kev tsim qauv muaj nuj nqi nyob rau hauv lub cell phab ntsa los yog daim nyias nyias raws li receptors. Raws li IUPAC txhais rau glycoproteins , a glycoprotein yog ib qho conjugate uas muaj carbohydrate (los yog glycan) covalently txuas rau cov protein.
Pom zoo:
Lub luag haujlwm ntawm CDK yog dab tsi hauv lub cev ua haujlwm ntawm tes tshwj xeeb hauv lub voj voog ntawm tes?
Los ntawm phosphorylation, Cdks teeb liab lub xov tooj ntawm tes uas nws tau npaj kom dhau mus rau theem tom ntej ntawm lub voj voog ntawm tes. Raws li lawv lub npe qhia, Cyclin-Dependent Protein Kinases yog nyob ntawm cyclins, lwm chav kawm ntawm kev tswj hwm cov protein. Cyclins khi rau Cdks, ua kom cov Cdks rau phosphorylate lwm cov molecules
Lub luag haujlwm ntawm plasma membrane proteins yog dab tsi?
Membrane cov nqaijrog yuav ua raws li enzymes rau kom tshuaj haum, ua raws li receptors rau tej molecules, los yog thauj ntaub ntawv thoob plaws hauv lub cell daim nyias nyias. Carbohydrates, los yog suab thaj, qee zaum pom txuas nrog cov proteins lossis lipids sab nraud ntawm lub cell membrane
Lub luag haujlwm ntawm lub cev muaj zog proteins yog dab tsi?
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Lub luag haujlwm ntawm daim nyias nyias thauj proteins yog dab tsi?
Kev thauj cov proteins ua lub qhov rooj rau ntawm tes, pab qee cov molecules hla rov qab mus rau hauv cov plasma membrane, uas nyob ib puag ncig txhua lub cell. Nyob rau hauv passive thauj molecules txav los ntawm ib cheeb tsam ntawm siab concentration mus rau qhov chaw uas tsis muaj concentration
Cov txheej txheem dab tsi yog lub luag haujlwm rau txoj haujlwm ua haujlwm sib txawv?
Position-effect variegation (PEV) tshwm sim thaum cov noob ib txwm nyob hauv euchromatin yog sib xyaw nrog heterochromatin los ntawm kev hloov kho lossis hloov pauv. Thaum lub ntim ntim heterochromatin kis thoob plaws heterochromatin / euchromatin ciam teb, nws ua rau kev hloov pauv ntawm kev ntsiag to hauv tus qauv stochastic