Dab tsi amino acid stabilizes tertiary qauv ntawm cov protein?
Dab tsi amino acid stabilizes tertiary qauv ntawm cov protein?

Video: Dab tsi amino acid stabilizes tertiary qauv ntawm cov protein?

Video: Dab tsi amino acid stabilizes tertiary qauv ntawm cov protein?
Video: Protein Structure and Folding 2024, Kaum ib hlis
Anonim

Cov kev sib cuam tshuam no yog ua tau los ntawm folding rau cov saw hlau kom coj cov amino acids nyob ze ze ua ke. 2. Tertiary qauv yog stabilized los ntawm disulfide bonds, ionic kev sib tshuam, hydrogen bonds , metallic bonds, thiab hydrophobic interactions.

Yog li ntawd, dab tsi kev sib cuam tshuam stabilize lub tertiary qauv ntawm ib tug protein?

Lub zog loj stabilizing tus qauv tertiary yog kev sib cuam tshuam ntawm hydrophobic ntawm nonpolar sab chains hauv cov tub ntxhais ntawm cov protein. Ntxiv stabilizing rog muaj xws li electrostatic kev sib cuam tshuam ntawm ionic pawg ntawm cov nqi rov qab, hydrogen bonds ntawm pawg polar, thiab disulfide daim ntawv cog lus.

Ib tug kuj yuav nug, leej twg ntawm cov amino acids no koom nrog covalent bonding uas stabilizes tertiary qauv ntawm ntau cov proteins? Raws li nrog disulfide choj, cov no hydrogen bonds tuaj yeem nqa ob feem ntawm cov saw hlau uas nyob deb deb ntawm qhov sib lawv liag. Cov choj ntsev, kev sib cuam tshuam ionic ntawm qhov zoo thiab qhov tsis zoo ntawm qhov chaw ntawm cov amino acid sab chains, kuj pab kom ruaj khov rau cov qauv tertiary ntawm cov protein.

Ua raws li qhov no hauv kev txiav txim siab, yuav ua li cas cov amino acids cuam tshuam rau cov qauv tertiary ntawm cov protein?

Ib zaug lub nonpolar amino acids tau tsim lub nonpolar core ntawm lub protein ntau , qaug zog van der Waals rog stabilize lub protein ntau . Tsis tas li ntawd, hydrogen bonds thiab ionic kev sib cuam tshuam ntawm cov polar, raug them amino acids pab txhawb rau tertiary qauv.

Cov qauv tertiary ntawm cov protein khaws cia li cas?

Kev piav qhia: Tertiary qauv yog ruaj khov los ntawm ntau yam kev sib cuam tshuam, tshwj xeeb yog cov pab pawg ua haujlwm sab hauv uas koom nrog hydrogen bonds , ntsev choj, covalent disulfide bonds , thiab hydrophobic kev sib cuam tshuam.

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