Lub zog twg yog qhov muaj feem cuam tshuam tshaj plaws hauv kev txiav txim siab tertiary qauv ntawm cov protein?

2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36

Lub tertiary qauv ntawm ib tug protein yog peb seem ntawm cov protein. Disulfide daim ntawv cog lus, hydrogen bonds , ionic daim ntawv cog lus , thiab kev sib cuam tshuam hydrophobic tag nrho cuam tshuam rau cov duab ntawm cov protein.

Raws li, dab tsi txiav txim siab tus qauv tertiary ntawm cov protein?

Protein tertiary qauv yog qhov peb seem ntawm a protein ntau . Cov tertiary qauv yuav muaj ib txoj hlua polypeptide "caj qaum" nrog ib lossis ntau dua protein ntau theem nrab cov qauv , cov protein ntau thaj chaw. Kev sib cuam tshuam thiab kev sib raug zoo ntawm cov saw hlau sab hauv ib qho tshwj xeeb protein txiav txim nws tertiary qauv.

Tsis tas li ntawd, vim li cas cov qauv tertiary ntawm cov protein tseem ceeb? Tertiary qauv yog tseem ceeb ! Cov kev ua haujlwm ntawm cov protein (tshwj tsis yog zaub mov) nyob ntawm nws tertiary qauv . Yog tias qhov no cuam tshuam, lub protein ntau tau hais tias yog denatured [Kev Sib Tham], thiab nws poob nws txoj haujlwm. denatured enzymes poob lawv lub zog catalytic.

Nyob rau hauv kev hwm rau qhov no, dab tsi yog lub zog loj tswj tertiary protein qauv?

Lub zog loj stabilizing tus qauv tertiary yog kev sib cuam tshuam ntawm hydrophobic ntawm nonpolar sab chains hauv cov tub ntxhais ntawm cov protein. Ntxiv stabilizing rog muaj xws li electrostatic kev sib cuam tshuam ntawm ionic pawg ntawm cov nqi rov qab, hydrogen bonds ntawm polar pawg, thiab disulfide bonds.

Dab tsi amino acid stabilizes tertiary qauv ntawm cov protein?

Kev tsim ntawm cov txuas hniav disulfide los ntawm oxidation ntawm sulfhydryl pawg ntawm cysteine yog ib qho tseem ceeb ntawm stabilization ntawm protein tertiary qauv , tso cai rau qhov sib txawv ntawm cov protein ntau saw yuav tuav ua ke covalently. Tsis tas li ntawd, hydrogen bonds tuaj yeem tsim los ntawm cov pab pawg sab nraud sib txawv.