Dab tsi yog qhov sib lawv liag ntawm cov strand tshiab tsim los ntawm DNA polymerase?
Dab tsi yog qhov sib lawv liag ntawm cov strand tshiab tsim los ntawm DNA polymerase?

Video: Dab tsi yog qhov sib lawv liag ntawm cov strand tshiab tsim los ntawm DNA polymerase?

Video: Dab tsi yog qhov sib lawv liag ntawm cov strand tshiab tsim los ntawm DNA polymerase?
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Txij li thaum DNA polymerase yuav tsum muaj 3 'OH pab pawg pub dawb rau kev pib ntawm kev sib txuas, nws tuaj yeem ua ke rau hauv ib qho kev taw qhia los ntawm kev nthuav tawm 3' kawg ntawm cov saw hlau nucleotide preexisting. Vim li no, DNA polymerase txav raws tus qauv txoj hlua nyob rau hauv ib tug 3'-5' kev taw qhia, thiab tus ntxhais txoj hlua yog tsim nyob rau hauv ib txoj kev 5'-3'.

Ua raws li qhov no saib, dab tsi ua rau DNA strand tshiab ntxiv rau qhov qub strand?

Cov enzyme DNA polymerase txav raws qhov raug strands thiab ntxiv ntxiv nucleotides rau txhua nucleotide hauv txhua qhov uas twb muaj lawm txoj hlua . A complementary strand yog tsim rau txhua tus ntawm ob strands ntawm tus thawj ob helix. d. Ob tshiab zoo ib yam DNA molecules tau tsim.

Ib qho tseem yuav nug, dab tsi xav tau ua ntej DNA polymerase synthesis ntawm DNA tshiab? RNA primer. xav tau ua ntej DNA polymerase synthesis ntawm DNA tshiab strand / ntxiv ntawm DNA tshiab nucleotides. qhov tseem ceeb. tsim RNA primers.

Tsis tas li ntawd, dab tsi yog cov kauj ruam rau DNA replication?

Muaj peb lub ntsiab cov kauj ruam rau DNA replication : pib, elongation, thiab termination. Txhawm rau kom haum rau hauv lub cell lub nucleus, DNA yog ntim rau hauv nruj coiled qauv hu ua chromatin, uas loosens ua ntej rov ua dua , tso cai rau lub cell rov ua dua machinery nkag mus rau lub DNA strands.

Vim li cas DNA polymerase mus ntawm 5 mus rau 3?

DNA replication mus rau hauv 5' rau 3 ' direction vim DNA polymerase ua rau ntawm 3 '-OH ntawm cov hlua uas twb muaj lawm rau kev ntxiv cov nucleotides dawb. DNA replications xav tau ib qhov chaw ntawm lub zog mus ntxiv xws li tsim cov phosphodiester bonds, lub zog no tau txais los ntawm cleaving triphosphate pawg ntawm nucleotide.

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