Lub nuclear lamina nyob qhov twg?

2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36

Cov nuclear lamina yog nyob nruab nrab ntawm sab hauv nuclear membrane thiab peripheral chromatin. Nws yog tsim los ntawm nuclear lamins thiab lamina - cov protein sib txuas. Cov nuclear lamina yog koom nrog nuclear lub koom haum, kev tswj lub voj voog ntawm tes, thiab kev sib txawv.

Hauv qhov no, dab tsi yog nuclear lamina?

Cov nuclear lamina yog ib qhov ntom ntom (~ 30 mus rau 100 nm tuab) fibrillar network hauv cov nucleus ntawm cov hlwb feem ntau. Nws yog tsim los ntawm intermediate filaments thiab membrane txuam nrog cov proteins. Dhau li muab kev pab kho tshuab, lub nuclear lamina tswj cov xwm txheej tseem ceeb ntawm tes xws li DNA replication thiab cell division.

Kuj Paub, puas yog nuclear lamina zoo ib yam li ER? Cov Nuclear Lamina thiab Nws Cov Haujlwm hauv Cov Nucleus Cov lub hnab ntawv nuclear yog ib tug tshwj xeeb subcompartment ntawm lub ER . Sab nrauv nuclear membrane yog nruam nrog peripheral ntxhib thiab du ER thiab zoo li biochemically thiab functionally zoo sib xws rau bulk ER daim nyias nyias.

Tsis tas li lo lus nug yog, qhov twg muaj cov kab mob nuclear pom?

Cov nuclear lamina yog meshwork ntawm nuclear intermediate filaments tsim los ntawm A- thiab B-hom lamins , nyob feem ntau nyob ze ntawm lub puab membrane ntawm lub nuclear hnab ntawv, tab sis kuj pom nyob rau theem qis hauv nucleoplasm (Dittmer & Misteli, 2011).

Cov nroj tsuag puas muaj nuclear lamina?

Cov nuclear lamina yog ib tug complex protein mesh txuas rau sab hauv nuclear membrane (INM), uas yog txuam nrog nuclear pore complexes. Ntxiv mus, txawm tias nroj tsuag tsis muaj lamin noob thiab cov noob encoding feem ntau lamin-binding proteins, lub luag haujlwm tseem ceeb ntawm lamina tau ua tiav hauv nroj tsuag.