Cov txheej txheem:

Cov txheej txheem dab tsi uas tus kws tshawb fawb siv los tsim ntau cov ntawv luam ntawm DNA xav tau sau rau hauv daim ntawv dawb paug 1?
Cov txheej txheem dab tsi uas tus kws tshawb fawb siv los tsim ntau cov ntawv luam ntawm DNA xav tau sau rau hauv daim ntawv dawb paug 1?

Video: Cov txheej txheem dab tsi uas tus kws tshawb fawb siv los tsim ntau cov ntawv luam ntawm DNA xav tau sau rau hauv daim ntawv dawb paug 1?

Video: Cov txheej txheem dab tsi uas tus kws tshawb fawb siv los tsim ntau cov ntawv luam ntawm DNA xav tau sau rau hauv daim ntawv dawb paug 1?
Video: Tshuaj theem vim li cas thiaj tau nqi ?/ Siv kho mob dab tsi?/paris polyphylla use for? 2024, Kaum ib hlis
Anonim

Molecular Cloning. Cloning tso cai rau cov creation ntawm ntau daim ntawv luam ntawm cov noob, kev qhia ntawm cov noob, thiab kev kawm txog cov noob caj noob ces. Kom tau txais cov DNA fragment rau hauv ib tug kab mob cell nyob rau hauv ib daim ntawv uas yuav tau theej los yog nthuav tawm, qhov tawg yog thawj zaug tso rau hauv plasmid.

Ib yam li ntawd, puas yog ib txoj hauv kev sib cais DNA tawg ntawm qhov loj me txhawm rau pab peb ua DNA rov ua dua?

Gel electrophoresis yog ib txoj kev siv rau cais DNA fragments raws li lawv qhov loj . DNA cov qauv raug thauj mus rau hauv qhov dej (indentations) ntawm ib qho kawg ntawm ib lub gel, thiab cov hluav taws xob tam sim no yog siv los rub lawv los ntawm cov gel. DNA tawg raug them tsis zoo, yog li lawv txav mus rau qhov zoo electrode.

Cov piv txwv ntawm DNA technology yog dab tsi? Piv txwv ntawm DNA technologies

  • DNA cloning. Hauv DNA cloning, cov kws tshawb fawb "clone" - ua ntau cov ntawv luam ntawm - DNA feem ntawm kev txaus siab, xws li cov noob.
  • Polymerase chain reaction (PCR).
  • Gel electrophoresis.
  • DNA sequencing.

Kuj nug, dab tsi cloning vector tshwj xeeb yog siv los qhia DNA rau cov nroj tsuag?

Qhov tseeb, tsuas yog ib daim me me ntawm Ti plasmid yog muab tso rau hauv lub cog genome-cov khoom no hu ua T DNA (rau pauv DNA ). The Ti plasmid yog ib tug natural vector uas niaj zaus ntxig tshiab DNA rau hauv cog hlwb.

Dab tsi yog 4 kauj ruam ntawm noob cloning?

Nyob rau hauv classical txwv enzyme digestion thiab ligation cloning raws tu qauv, cloning ntawm tej DNA fragment yeej tseem ceeb muaj plaub kauj ruam:

  • Kev cais tawm ntawm DNA ntawm kev txaus siab (lossis lub hom phiaj DNA),
  • kev ligation,
  • transfection (los yog transformation), thiab.
  • ib txoj kev tshuaj ntsuam/xaiv.

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