Alu TPA sequence yog dab tsi?
Alu TPA sequence yog dab tsi?

Video: Alu TPA sequence yog dab tsi?

Video: Alu TPA sequence yog dab tsi?
Video: Koj yog luag tus los kuv tseem nco. 4/27/2018 2024, Kaum ib hlis
Anonim

chromosome, txhawm rau nrhiav qhov ntxig ntawm DNA luv ib ntus , npe Alu , nyob rau hauv. cov ntaub so ntswg plasminogen activator ( TPA ) noob. Alu Cov ntsiab lus tau muab cais ua SINEs, lossis luv INterspersed Elements.

Tib neeg kuj nug, qhov ua haujlwm ntawm Alu yog dab tsi?

Alu cov ntsiab lus yog lub luag haujlwm rau kev tswj cov ntaub so ntswg tshwj xeeb. Lawv kuj tseem koom nrog hauv kev hloov pauv ntawm cov noob nyob ze thiab qee zaum tuaj yeem hloov pauv txoj kev gene qhia. Alu cov ntsiab lus yog retrotransposons thiab zoo li DNA luam los ntawm RNA polymerase III-encoded RNAs.

Ib tug kuj nug, koj genotype rau Alu noob yog dab tsi? Cov noob caj noob ces Keeb kwm. Qhov kev sim no tshuaj xyuas PV92, tib neeg tshwj xeeb Alu tso rau ntawm chromosome 16. Lub PV92 caj ces system tsuas muaj ob qho alleles qhia tias muaj (+) lossis tsis muaj (-) ntawm qhov Alu transposable element ntawm txhua tus khub chromosomes. Qhov no ua rau peb PV92 genotypes (++, +-, lossis --).

Xav txog qhov no, ntev npaum li cas ntawm Alu sequence?

Alu sequences yog rov ua dua DNA Kev pom zoo Alu sequences yog kwv yees li 280 bp in ntev , thiab muaj ob yam zoo sib xws, tab sis txawv monomers txuas los ntawm ib qho oligo-d(A) tract (Fig. 1). Txoj cai Alu monomer muaj 31 bp ntxig tsis tuaj ntawm sab laug monomer.

Alu PCR yog dab tsi?

Alu PCR yog ib qho kev ceev thiab yooj yim-rau-ua "DNA ntiv tes" cov txheej txheem raws li kev soj ntsuam ib txhij ntawm ntau cov genomic loci flanked los ntawm Alu Cov ntsiab lus rov ua dua, uas tso cai rau kev tshawb nrhiav cov noob caj noob ces polymorphisms thiab kev hloov pauv hauv tib neeg thiab primate genomes.

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