Video: Lub luag haujlwm ntawm RecA yog dab tsi?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
RecA yog 38 kilodalton protein tseem ceeb rau kev kho thiab kho DNA. RecA cov Kev koom tes nrog DNA loj yog nyob ntawm nws lub hauv paus luag hauj lwm nyob rau hauv homologous recombination. Cov RecA protein khi ruaj khov thiab nyob rau hauv pawg ntev rau ssDNA los tsim cov nucleoprotein filament.
Hauv qhov no, kev ua haujlwm ntawm Rec A protein yog dab tsi?
RecA yog kab mob protein ntau uas muaj nuj nqi tsawg kawg yog ob txoj hauv kev los kho DNA puas. Ua ntej, nws muaj DNA strand pauv kev ua si uas catalyzes recombinational DNA kho. Qhov thib ob, nws muaj cov haujlwm coprotease uas tswj cov kev qhia ntawm SOS noob uas tseem koom nrog hauv DNA kho.
Tsis tas li ntawd, muaj pes tsawg DNA binding qhov chaw puas muaj RecA filament? Qhov no filament ntawm RecA , muaj a DNA molecule nyob rau hauv nws sab hauv, tau khi lwm DNA molecule thiab tseem yog ib feem peb nyob rau hauv lub xub ntiag ntawm cofactor (ATP los yog nws cov analogs). Txhua filament muaj muaj peb DNA khi qhov chaw , txhua tus muaj peev xwm khi ib DNA strand ntawm ss lossis ds DNA.
Ib sab saum toj no, RecA txhais li cas?
Txhais. RECA. Recombination Protein A. RECA. Radiation Exposure Compensation Act ntawm 1990.
Thaum puas los yog ib leeg stranded DNA activates RecA Protein Cov RecA protein nkoos lub cleavage ntawm LexA Qhov no tshwm sim?
Cov RecA protein , txhawb nqa los ntawm ib leeg - tso tseg DNA , yog koom nrog inactivation ntawm repressor ( LexA ) ntawm SOS teb cov noob yog li inducing cov lus teb. Nws yog ib qho kev ua yuam kev-nrhiav kev kho uas muaj txiaj ntsig zoo rau DNA Kev hloov pauv tau pom nyob rau hauv ntau hom.
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