Video: Puas yog oxidative decarboxylation ntawm pyruvate synthesize ATP?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Thaum kawg ntawm glycolysis, peb muaj ob pyruvate ua molecules uas tseem muaj ntau lub zog extractable. Pyruvate oxidation yog cov kauj ruam tom ntej nyob rau hauv kev ntes cov seem zog nyob rau hauv daim ntawv ntawm ATP pib ntawv, A, T, P, cov ntawv kawg, txawm tias tsis muaj ATP pib ntawv, A, T, P, ntawv kawg yog ua ncaj qha thaum lub sij hawm pyruvate oxidation.
Ua kom pom qhov no, yuav ua li cas thaum lub sij hawm oxidative decarboxylation ntawm pyruvate?
Cov txheej txheem ntawm kev hloov pauv pyruvate ua rau acetyl-CoA yog ib qho oxidative decarboxylation . Cov tshuaj tiv thaiv no suav nrog kev hloov hluav taws xob los ua NADH, decarboxylation ntawm pyruvate , thiab tsim ntawm actetyl-CoA, ib qho activated ob carbon compound.
Kuj Paub, cov khoom ntawm pyruvate oxidation yog dab tsi? Thawj oxidation kauj ruam pib nrog ib tug molecule ntawm pyruvate ua thiab ua rau kev tsim cov CO2, electrons, thiab acetyl CoA. Thaum lub sij hawm thib ob, hu ua Krebs cycle, ib qho molecule ntawm acetyl CoA ntxiv oxidized . Cov txiaj ntsig ntawm cov kauj ruam no suav nrog ntau cov electrons, ob lub molecules ntawm CO2, thiab ib qho ATP.
Tsis tas li ntawd, ntau npaum li cas ATP raug tsim nyob rau hauv pyruvate oxidation?
Thaum lub sijhawm them nyiaj ntawm glycolysis, plaub pawg phosphate raug xa mus rau ADP los ntawm substrate-theem phosphorylation los ua plaub. ATP , thiab ob NADH yog ua thaum lub pyruvate ua yog oxidized.
Yuav ua li cas molecules tsim ATP los ntawm oxidative phosphorylation?
Glycolysis tsim tsuas yog 2 ATP molecules, tab sis qhov chaw ntawm 30 thiab 36 ATPs yog tsim los ntawm oxidative phosphorylation ntawm 10. NADH thiab 2 succinate molecules ua los ntawm kev hloov ib qho molecule ntawm qabzib mus rau carbon dioxide thiab dej, thaum txhua lub voj voog ntawm beta oxidation ntawm fatty acid yields txog 14 ATPs.
Pom zoo:
Puas yog oxidative phosphorylation zoo ib yam li electron thauj saw?
Oxidative phosphorylation yog tsim los ntawm ob qho kev sib txuas zoo sib xws: cov saw hlau thauj hluav taws xob thiab chemiosmosis. Hauv cov khoom siv hluav taws xob thauj khoom, cov khoom siv hluav taws xob tau dhau los ntawm ib lub molecule mus rau lwm qhov, thiab lub zog tso tawm hauv cov hluav taws xob hloov hluav taws xob no yog siv los tsim cov tshuaj electrochemical gradient
Muaj pes tsawg ATP yog tsim los ntawm ib tug pyruvate?
2 ATP Ib yam li ntawd, nws tau nug, pes tsawg ATP raug tsim los ntawm txhua pyruvate? Rau aerobic ua pa, nws yog hais txog 30 ATP rau 2 pyruv. Tag nrho txog 32 tag nrho net ATP yog tsim rau ib qabzib, tab sis 2 ntawm cov no yog los ntawm glycolysis, yog li tsis suav rau pyruvate ua .
Dab tsi yog txhais los ntawm oxidative phosphorylation?
Lub ntsiab lus ntawm oxidative phosphorylation: lub synthesis ntawm ATP los ntawm phosphorylation ntawm ADP rau lub zog yog tau los ntawm electron thauj thiab uas tshwm sim nyob rau hauv lub mitochondria thaum lub sij hawm aerobic ua pa
Dab tsi yog qhov flux los ntawm lub voos xwmfab ntawm sab yog tias tus nqi ntawm Q yog ntawm ib qho ntawm nws lub ces kaum?
Raws li peb paub tias, tag nrho cov flux los ntawm tus nqi q yog q / ε 0 (Gauss txoj cai). Yog hais tias tus nqi yog nyob rau ntawm lub ces kaum ntawm lub voos xwmfab, ib co ntawm cov flux nkag mus rau hauv lub voos xwmfab thiab tawm los ntawm ib co ntawm nws lub ntsej muag. Tab sis qee qhov flux tsis nkag mus rau hauv lub voos xwmfab. Qhov 1/8th no yuav muab faib ua 3 ntu dua
Yuav ua li cas muaj pes tsawg molecules ntawm carbon dioxide yog tsim thaum ib tug pyruvate molecule ua tiav los ntawm aerobic ua pa?
Lub yim kauj ruam ntawm lub voj voog yog cov tshuaj lom neeg cov tshuaj tiv thaiv uas ua rau cov hauv qab no los ntawm txhua qhov ntawm ob lub molecules ntawm pyruvate uas ua rau ib molecule ntawm qabzib uas tau pib mus rau hauv glycolysis (Daim duab 3): 2 carbon dioxide molecules. 1 ATP molecule (los yog sib npaug)