Puas yog oxidative decarboxylation ntawm pyruvate synthesize ATP?
Puas yog oxidative decarboxylation ntawm pyruvate synthesize ATP?

Video: Puas yog oxidative decarboxylation ntawm pyruvate synthesize ATP?

Video: Puas yog oxidative decarboxylation ntawm pyruvate synthesize ATP?
Video: Rapid Revision - Biochemistry | FMGE Jan 2023 | Dr. Azam 2024, Kaum ib hlis
Anonim

Thaum kawg ntawm glycolysis, peb muaj ob pyruvate ua molecules uas tseem muaj ntau lub zog extractable. Pyruvate oxidation yog cov kauj ruam tom ntej nyob rau hauv kev ntes cov seem zog nyob rau hauv daim ntawv ntawm ATP pib ntawv, A, T, P, cov ntawv kawg, txawm tias tsis muaj ATP pib ntawv, A, T, P, ntawv kawg yog ua ncaj qha thaum lub sij hawm pyruvate oxidation.

Ua kom pom qhov no, yuav ua li cas thaum lub sij hawm oxidative decarboxylation ntawm pyruvate?

Cov txheej txheem ntawm kev hloov pauv pyruvate ua rau acetyl-CoA yog ib qho oxidative decarboxylation . Cov tshuaj tiv thaiv no suav nrog kev hloov hluav taws xob los ua NADH, decarboxylation ntawm pyruvate , thiab tsim ntawm actetyl-CoA, ib qho activated ob carbon compound.

Kuj Paub, cov khoom ntawm pyruvate oxidation yog dab tsi? Thawj oxidation kauj ruam pib nrog ib tug molecule ntawm pyruvate ua thiab ua rau kev tsim cov CO2, electrons, thiab acetyl CoA. Thaum lub sij hawm thib ob, hu ua Krebs cycle, ib qho molecule ntawm acetyl CoA ntxiv oxidized . Cov txiaj ntsig ntawm cov kauj ruam no suav nrog ntau cov electrons, ob lub molecules ntawm CO2, thiab ib qho ATP.

Tsis tas li ntawd, ntau npaum li cas ATP raug tsim nyob rau hauv pyruvate oxidation?

Thaum lub sijhawm them nyiaj ntawm glycolysis, plaub pawg phosphate raug xa mus rau ADP los ntawm substrate-theem phosphorylation los ua plaub. ATP , thiab ob NADH yog ua thaum lub pyruvate ua yog oxidized.

Yuav ua li cas molecules tsim ATP los ntawm oxidative phosphorylation?

Glycolysis tsim tsuas yog 2 ATP molecules, tab sis qhov chaw ntawm 30 thiab 36 ATPs yog tsim los ntawm oxidative phosphorylation ntawm 10. NADH thiab 2 succinate molecules ua los ntawm kev hloov ib qho molecule ntawm qabzib mus rau carbon dioxide thiab dej, thaum txhua lub voj voog ntawm beta oxidation ntawm fatty acid yields txog 14 ATPs.

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