Koj lub genotype rau Alu gene yog dab tsi?
Koj lub genotype rau Alu gene yog dab tsi?

Video: Koj lub genotype rau Alu gene yog dab tsi?

Video: Koj lub genotype rau Alu gene yog dab tsi?
Video: tsuav koj muaj lub suab luag - Mana Xiong 2024, Kaum ib hlis
Anonim

PV 92 caj ces system tsuas muaj ob qho alleles qhia tias muaj (+) lossis tsis muaj (-) ntawm qhov Alu transposable element ntawm txhua tus khub chromosomes. Qhov no ua rau peb PV92 genotypes (++, +-, lossis --). Tib neeg chromosomes muaj txog 1,000,000 Alu cov ntawv luam, uas sib npaug 10% ntawm tag nrho cov genome.

Tsuas yog li ntawd, nws txhais li cas yog tias koj muaj ALU noob?

Alu cov ntsiab lus yog lub luag haujlwm rau kev tswj cov ntaub so ntswg tshwj xeeb noob . Lawv tseem muaj kev koom tes nyob rau hauv transcription ntawm ze noob thiab ua tau qee zaum hloov txoj kev a noob yog qhia. Alu cov ntsiab lus yog retrotransposons thiab zoo li DNA luam los ntawm RNA polymerase III-encoded RNAs.

Kuj Paub, dab tsi yog lub noob pv92? Cov PV92 ua Lub cheeb tsam DNA, los yog chaw , uas koj yuav luam yog hu ua PIB 92 . Cov PV92 ua yog ib feem ntawm ib qho intron ntawm chromosome 16. Pom tau tias, ntu no ntawm cov DNA uas tsis yog coding tau muab luam tawm ntau zaus thaum lub sij hawm hloov pauv ntawm cov primates, thiab muab tso rau hauv genome ntawm ntau qhov chaw.

Ib yam li ntawd, tib neeg nug, dab tsi yog Alu cov ntsiab lus hauv tib neeg genome?

Ib Alu element (los yog yooj yim, " Alu ”) yog transposable keeb , tseem hu ua "jumping gene." Hloov tau cov ntsiab lus yog qhov tsis tshua muaj tshwm sim ntawm DNA uas tuaj yeem txav mus (lossis hloov pauv) lawv tus kheej mus rau txoj haujlwm tshiab hauv genome ntawm ib lub cell. Alu ntsiab muaj txog 300 lub hauv paus ntev thiab pom thoob plaws hauv lub tib neeg genome.

Lub luag haujlwm dab tsi ua Alu cov ntsiab lus ua si hauv kev tswj cov noob hauv tib neeg?

Alu ntsiab yog 7SL RNA zoo li SINEs (Deininger, 2011). Raws li cov qauv tsim thiab ntau yam haujlwm, Alu ntsiab tuaj yeem koom nrog hauv kev cai ntawm gene qhia thiab tej zaum yuav cuam tshuam rau kev qhia ntawm ntau noob los ntawm kev ntxig rau hauv lossis ze ntawm noob txhawb cheeb tsam.

Pom zoo: