Oxaloacetate rov qab li cas?
Oxaloacetate rov qab li cas?

Video: Oxaloacetate rov qab li cas?

Video: Oxaloacetate rov qab li cas?
Video: Lecture 14C: The Role of the Citric Acid Cycle in Metabolism 2024, Kaum ib hlis
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Ib txoj hauv kev tseem ceeb uas tib neeg cov hlwb thiab lwm cov kab mob mammalian ntxiv cov intermediates yog los ntawm Ntxiv oxaloacetate ; Qhov no yog ua los ntawm carboxylatingpyruvate rau hauv oxaloacetate hmoov Los ntawm cov txheej txheem uas catalyzed los ntawm ib qho enzyme hu ua pyruvate carboxylase.

Xav txog qhov no, Oxaloacetate rov tsim dua li cas?

Oxaloacetate yog ces rov tsim dua tshiab los ntawm succinate. Ob lub pa roj carbon atom nkag mus rau hauv lub voj voog raws li acetyl chav tsev thiab ob lub pa roj carbon atom tawm hauv lub voj voog nyob rau hauv daim ntawv ntawm ob lub molecules ntawm carbon dioxide. Lub luag haujlwm ntawm lub voj voog citric acid yog khaws cov hluav taws xob hluav taws xob siab los ntawm cov roj carbon.

Ib tug kuj yuav nug, yuav ua li cas yog citric acid voj voog? Citric Acid Cycle -Acetyl-CoA to CO citric acid voj voog (CAC) lees txais 2-carbon acetyl-CoAmolecule thiab oxidizes tag nrho rau CO2 thiab H2O. Zog tau txais peb hom: NADH, FADH2, thiab GTP.

Kuj Paub, Oxaloacetate yog dab tsi?

Qhov pib ntawm cov txheej txheem no tshwm sim hauv themitochondrial matrix, qhov twg pyruvate molecules pom. Apyruvate molecule yog carboxylated los ntawm pyruvate carboxylase enzyme, qhib los ntawm ib tug molecule txhua ntawm ATP thiab dej. Qhov no reactionresults nyob rau hauv lub tsim ntawm oxaloacetate hmoov . NADH txo oxaloacetate hmoov ua malate.

Vim li cas pyruvate hloov mus rau Oxaloacetate?

Es, oxaloacetate hmoov yog tsim los ntawm cov carboxylation ntawm pyruvate ua , hauv cov tshuaj tiv thaiv catalyzed los ntawm thebiotin-dependent enzyme pyruvate ua carboxylase. Nco qab tias qhov enzyme no ua lub luag haujlwm tseem ceeb hauv gluconeogenesis (Section16.3.2). Yog hais tias tus nqi zog yog siab, oxaloacetate hmoov yog hloov dua siab tshiab rau hauv qabzib.

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