Video: Vim li cas Thermogenin yog ib qho tseem ceeb ntawm cov protein?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Thaum no protein ntau , thermogenin , yog nquag, mitochondria tsim cov cua sov ntau dua li ATP. Tus founder ntawm tsev neeg, thermogenin , tau renamed uncoupling protein ntau 1 lossis UCP1 thiab paub tias yog tseem ceeb hauv kev pab tsiaj kom sov thaum hibernation thiab rau cov menyuam mos kom tswj tau lawv lub cev kub.
Ib yam li ntawd, qhov tseem ceeb ntawm uncoupling proteins nyob rau hauv cov ntaub so ntswg adipose yog dab tsi?
Abstract. Uncoupling cov protein (UCPs) yog cov mitochondrial transporters uas muaj nyob rau hauv daim nyias nyias ntawm mitochondria. Lub sij hawm uncoupling protein ” yog Ameslikas siv rau UCP1, uas yog tshwj xeeb tam sim no nyob rau hauv mitochondria ntawm xim av adipocytes, thermogenic hlwb uas tswj lub cev kub nyob rau hauv me me nas.
Tom qab ntawd, lo lus nug yog, cov proteins uas tsis sib txuas ua li cas? Ib uncoupling protein (UCP) yog mitochondrial inner membrane protein ntau uas yog tswj hwm proton channel lossis transporter. Ib uncoupling protein yog li muaj peev xwm ntawm dissipating proton gradient generated los ntawm NADH-powered pumping protons los ntawm mitochondrial matrix mus rau mitochondrial interemembrane qhov chaw.
Hais txog qhov no, ua haujlwm ntawm Thermogenin yog dab tsi?
Uncoupling protein (UCP) los yog thermogenin yog 33 kDa puab-membrane mitochondrial protein tshwj xeeb rau xim av adipocytes hauv cov tsiaj txhu uas muaj nuj nqi Raws li ib tug proton transporter, tso cai rau lub dissipation raws li tshav kub ntawm lub proton gradient generated los ntawm lub pa saw thiab yog li uncoupling oxidative phosphorylation.
Thermogenin nyob qhov twg thiab nws lub hom phiaj yog dab tsi?
Thermogenin ua haujlwm tom qab khi rau purine nucleotides, uas GDP yog tus zoo tshaj plaws thiab ADP thiab ATP tsis tshua muaj txiaj ntsig. Cov protein no recouples phosphorylation nrog tus zog tso tawm rau hauv tus txoj hlab pa. Nws yog nyob ntawm tus nkag rau tus H+ channel rau tus C sab tus sab hauv daim nyias nyias.
Pom zoo:
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