Dab tsi yuam kev tuaj yeem tshwm sim hauv DNA replication?

2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36

Cov hom no yuam kev suav nrog depurination, uas tshwm sim Thaum daim ntawv cog lus txuas nrog purine rau nws cov piam thaj deoxyribose tawg los ntawm cov dej molecule, ua rau muaj purine-dawb nucleotide uas ua tau ' tsis ua raws li tus qauv thaum lub sij hawm DNA replication , thiab deamination, uas ua rau poob ntawm pawg amino los ntawm nucleotide, Hauv qhov no, pes tsawg qhov yuam kev tshwm sim hauv DNA replication?

Nws yog kwv yees tias replicate eukaryotic DNA polymerases ua yuam kev kwv yees li ib zaug txhua 10⁴ – 10⁵ nucleotides polymerized [58, 59]. Yog li, txhua lub sij hawm ib tug diploid mammalian cell replicates, tsawg kawg yog 100,000 thiab mus txog 1,000,000 polymerase yuam kev tshwm sim.

Qhov thib ob, yuav ua li cas thaum DNA tsis rov ua kom raug? Yog cell tsis muaj kom luam nws cov chromosomes los yog muaj yog kev puas tsuaj rau DNA , CDK yuav tsis yog qhib lub S theem cyclin thiab lub cell yuav tsis yog nce mus rau theem G2. Lub cell yuav nyob twj ywm hauv S theem mus txog thaum chromosomes yog luam tau zoo, lossis lub xovtooj ntawm tes yuav raug programmed cell tuag.

Kuj paub, vim li cas qhov yuam kev hauv DNA replication tsis tshua muaj?

Cov yuam kev hauv DNA replication yog tsawg heev vim cov ntaub ntawv pov thawj kev nyeem ntawv, uas tswj kev ncaj ncees ntawm DNA replication . Thaum DNA replication , cov enzyme DNA polymerase III qhia txog kev sib koom ua ke ua ke rov qab mus rau lub hauv paus ntawm cov qauv strand.

Yuav ua li cas thaum DNA puas lawm?

Cov DNA nyob rau hauv ib qho ntawm koj lub hlwb tau txais puas lawm kaum tawm txhiab zaus hauv ib hnub. Vim DNA muab cov qauv qhia rau cov proteins uas koj lub hlwb xav tau ua haujlwm, qhov no kev puas tsuaj tuaj yeem ua rau muaj teeb meem loj-xws li mob qog noj ntshav. Hmoov zoo, koj lub hlwb muaj txoj hauv kev kho feem ntau ntawm cov teeb meem no, feem ntau ntawm lub sijhawm.