Cov txheej txheem:
Video: Cov kab mob dab tsi tshwm sim los ntawm Nondisjunction?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Kev tsis sib haum xeeb ua rau Qhov yuam kev hauv chromosome tooj, xws li trisomy 21 (Down syndrome) thiab monosomy X (Turner syndrome). Nws kuj yog ib yam ua rau ntawm thaum ntxov spontaneous rho menyuam.
Ua li no, Nondisjunction yog dab tsi thiab thaum twg nws tshwm sim?
Kev tsis sib haum xeeb txhais tau hais tias ib khub ntawm homologous chromosomes tsis tau cais los yog cais ntawm anaphase kom ob qho tib si chromosomes ntawm khub dhau mus rau tib tus ntxhais cell. Qhov no tej zaum tshwm sim Feem ntau nyob rau hauv meiosis, tab sis nws yuav tshwm sim hauv mitosis los tsim ib tus neeg mosaic.
Ib sab saum toj no, Nondisjunction ua rau Down syndrome li cas? TUG 21 ( NONDISJUNCTION ) Down syndrome feem ntau yog tshwm sim los ntawm kev ua yuam kev hauv cell division hu ua kev tsis sib haum xeeb .” Kev tsis sib haum xeeb ua rau lub embryo nrog peb daim ntawv theej ntawm chromosome 21 es tsis txhob siv ob qho tib si. Ua ntej los yog thaum xeeb tub, ib khub ntawm 21st chromosomes nyob rau hauv cov phev los yog lub qe tsis cais.
Ib yam li ntawd, tib neeg nug, qee qhov piv txwv ntawm Nondisjunction disorders yog dab tsi?
Cov ntsiab lus
- 3.1 Monosomy. 3.1.1 Turner Syndrome (X monosomy) (45, X0)
- 3.2 Autosomal trisomy. 3.2.1 Down Syndrome (trisomy 21)
- 3.3 Kev sib deev chromosome aneuploidy. 3.3.1 Klinefelter Syndrome (47, XXY)
- 3.4 Kev tsis sib haum xeeb.
- 3.5 Mosaicism syndromes.
- 3.6 Mosaicism nyob rau hauv malignant transformation.
Dab tsi yog 3 tib neeg kev mob tshwm sim los ntawm kev ua yuam kev hauv meiosis dab tsi txawv txav txhua tus muaj?
Trisomy, muaj peb, tsis yog ob, luam ntawm ib qho chromosome, ua rau Down syndrome , los yog trisomy 21, thiab tshwm sim hauv kwv yees li 1/800 yug nyob. Lwm yam trisomies muaj xws li trisomy 13 thiab 18. Mosaicism rau ib txwm cell kab thiab ib qho txawv txav ntawm tes yuav tshwm sim hauv ib tus neeg.
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