Dab tsi yog qhov ua haujlwm ntawm cov qib mob hnyav?

2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36

Qhov zoo-theem-theem proteins pab (raws li ib feem ntawm innate tiv thaiv kab mob ) sib txawv physiological functions nyob rau hauv lub tiv thaiv kab mob . Ib txhia ua kom puas los yog inhibit kev loj hlob ntawm microbes, piv txwv li, C-reactive protein, mannose-binding protein, ntxiv yam, ferritin, ceruloplasmin, serum amyloid A thiab haptoglobin.

Tsis tas li lo lus nug yog, yam khoom twg yog qhov mob hnyav theem protein?

Ob lub ntsiab tsis zoo mob theem proteins yog albumin thiab transferrin.

Tsis tas li ntawd, qhov twg feem ntau mob theem proteins ua ke? Mob theem proteins yog ua ke feem ntau nyob rau hauv lub siab. Hauv kev teb rau kev raug mob, cov hlwb hauv zos (neutrophil granulocytes thiab macrophages) zais ntau cov cytokines rau hauv cov hlab ntsha, feem ntau Qhov tseem ceeb ntawm cov no yog cov interleukins IL-1, IL-6 thiab IL-8, thiab TNF-α.

Tsis tas li ntawd, dab tsi ua rau cov lus teb rau theem mob hnyav?

Cov mob theem teb Nws tuaj yeem pib sai sai los ntawm kev tso tawm ntawm cov neeg nruab nrab rau hauv cov kev ncig tom qab stimulation ntawm hepatocytes nyob rau hauv daim siab los ntawm endogenous pyrogens IL-1, IL-6 thiab TNF-alpha tso tawm los ntawm activated macrophages.

Dab tsi yog acute phase serum?

Kev nce hauv qhov concentration ntawm ntshav qab zib proteins uas yog hu ua mob theem reactants (APR) nrog o thiab cov ntaub so ntswg raug mob [1, 2]. Mob theem proteins yog txhais raws li cov proteins uas nws ntshav qab zib concentrations nce los yog txo tsawg kawg yog 25 feem pua thaum lub xeev inflammatory [1].