Yuav ua li cas rau cov protein tom qab kev txhais lus?
Yuav ua li cas rau cov protein tom qab kev txhais lus?

Video: Yuav ua li cas rau cov protein tom qab kev txhais lus?

Video: Yuav ua li cas rau cov protein tom qab kev txhais lus?
Video: YUAV COJ LI CAS TU NEEG KOJ HLUB THIAJ NCO KOJ 2024, Kaum ib hlis
Anonim

Protein Folding

Tom qab tau txhais los ntawm mRNA, tag nrho cov proteins pib tawm ntawm ribosome raws li cov kab sib txuas ntawm cov amino acids. Ntau cov proteins quav spontaneously, tab sis ib co cov proteins xav tau tus pab molecules, hu ua chaperones, los tiv thaiv lawv los ntawm aggregating thaum lub sij hawm txoj kev nyuaj ntawm folding

Tsis tas li ntawd, cov protein mus qhov twg tom qab kev txhais lus?

Cov protein uas ua tsis muaj lub teeb liab peptide nyob hauv cytosol rau tus so txhais lus . Yog tias lawv tsis muaj lwm "cov ntawv sau npe," lawv yuav nyob hauv cytosol mus tas li. Txawm li cas los xij, yog tias lawv muaj cov ntawv sau zoo, lawv tuaj yeem xa mus rau mitochondria, chloroplasts, peroxisomes, lossis nucleus. tom qab kev txhais lus.

Yuav ua li cas thaum kawg ntawm kev txhais lus? Kev txhais lus xaus rau hauv tus txheej txheem hu ua kev txiav txim . Kev txiav txim yuav tshwm sim thaum nres codon hauv mRNA (UAA, UAG, lossis UGA) nkag mus rau A site. Nres codons raug lees paub los ntawm cov proteins hu ua cov khoom tso tawm, uas haum zoo rau hauv P site (tab sis lawv tsis yog tRNAs).

Tsis tas li ntawd, yuav ua li cas tom qab kev txhais lus ntawm cov protein synthesis?

Nyob rau hauv tus txheej txheem ntawm txhais lus , mRNA txuas rau lub ribosome. Tom ntej no , tRNA molecules shuttle cov amino acids tsim nyog rau ribosome, ib-los-ib, coded los ntawm sequential triplet codons ntawm mRNA, mus txog rau thaum protein ntau yog tag nrho ua ke . Thaum twg ua tiav, mRNA tshem tawm ntawm ribosome, thiab protein ntau tso tawm.

Yuav ua li cas rau cov protein tom qab lawv tsim?

Cov protein yog cov saw ntev ntawm cov amino acids, thiab tus raws nraim li cas ntawm tus amino acids txiav txim tus kawg qauv thiab muaj nuj nqi ntawm cov protein . Thaum kawg, thaum txiav tawm, tus ribosome unbinds los ntawm tus mRNA, thiab tus amino acid saw mus rau yuav tsum tau ua thiab folded ua tus kawg, ua haujlwm protein ntau.

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