Yuav ua li cas peptidoglycan synthesized?
Yuav ua li cas peptidoglycan synthesized?

Video: Yuav ua li cas peptidoglycan synthesized?

Video: Yuav ua li cas peptidoglycan synthesized?
Video: La Yang Ft. Phuab Vaj - Yuav Ua Li Cas [Official MV] 2024, Kaum ib hlis
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Biosynthesis. Cov peptidoglycan monomers yog ua ke nyob rau hauv lub cytosol thiab ces txuas mus rau ib tug membrane carrier bactoprenol. Bactoprenol thauj peptidoglycan monomers hla lub cell membrane qhov twg lawv muab tso rau hauv cov uas twb muaj lawm peptidoglycan.

Ntxiv rau qhov no, peptidoglycan biosynthesis yog dab tsi?

Cov biosynthesis ntawm cov kab mob cell phab ntsa peptidoglycan yog ib qho txheej txheem nyuaj uas cuam tshuam nrog cov tshuaj tiv thaiv enzyme uas tshwm sim hauv cytoplasm ( synthesis ntawm nucleotide precursors) thiab sab hauv ( synthesis ntawm lipid-txuas intermediates) thiab sab nraud (polymerization cov tshuaj tiv thaiv) ntawm cytoplasmic membrane.

Tsis tas li ntawd, peptidoglycan nyob qhov twg? Peptidoglycan (murein) yog ib qho tseem ceeb thiab tshwj xeeb ntawm cov phab ntsa ntawm cov kab mob pom nyob rau sab nraud ntawm cytoplasmic membrane ntawm yuav luag tag nrho cov kab mob (Rogers li al., 1980; Park, 1996; Nanninga, 1998; Mengin-Lecreulx & Lemaitre, 2005).

Ib yam li ib tug yuav nug, dab tsi tiv thaiv peptidoglycan synthesis?

Cov peptidoglycan cell phab ntsa ncig lub cytoplasmic membrane thiab tiv thaiv osmotic lysis. Peptidoglycan yog tsim los ntawm interlocking chains ntawm lub tsev blocks hu ua peptidoglycan cov monomers. Muaj ntau cov tshuaj tua kab mob inhibit peptidoglycan synthesis nyob rau hauv cov kab mob thiab ua rau osmotic lysis ntawm cov kab mob.

Cov qauv tshuaj ntawm peptidoglycan yog dab tsi?

Peptidoglycan yog ua los ntawm chains ntawm alternating molecules hu ua N-acetylglucosamine (NAG) thiab N-acetylmuramic acid (NAM). Thaum ob tug no molecules yog covalently bonded ua ke, nws yog hu ua ib tug glycan saw. Zoo li cov shingles ntawm peb lub ru tsev, tuaj yeem muaj ntau txheej ntawm glycan chains nyob rau hauv peptidoglycan txheej.

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