Video: Koj yuav npaj ethylamine los ntawm Gabriel phthalimide synthesis li cas?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Koj ua tau zoo tshaj plaws npaj ib tug thawj amine los ntawm nws cov alkylazide los ntawm kev txo los yog los ntawm cov Gabriel synthesis . Hauv Gabriel synthesis , poov tshuaj phthalimide yog reacted nrog alkyl halide los tsim N-alkyl phthalimide . Qhov no N-alkyl phthalimide tuaj yeem hydrolyzed los ntawm aqueous acids los yog hauv paus rau hauv thawj amine.
Tsis tas li ntawd, koj tuaj yeem tau txais ethyl amine los ntawm Gabriel phthalimide synthesis li cas?
Kev piav qhia: Gabriel phthalimide synthesis yog siv rau qhov kev npaj ntawm 1 ° amines . Qhov no suav nrog cov tshuaj tiv thaiv ntawm poov tshuaj ntsev ntawm phthalimide thiab tom qab ntawd nrog ethyl chloride ua raws li hydrolysis los tsim 1 ° amine . Cov tshuaj tiv thaiv rau cov synthesis ntawm ethyl amine yog muab rau hauv daim duab txuas hauv qab no.
Ib yam li ntawd, thawj amines tau npaj los ntawm Gabriel phthalimide synthesis li cas? Thaum Gabriel phthalimide synthesis , cov tshuaj tiv thaiv ntawm phthalimide thiab ethanolic potassium hydroxide muab potassium ntsev ntawm phthalimide . Cov ntsev ntawm cua sov nrog alkyl halide ua raws li alkaline hydrolysis muab coj los siv thawj amine.
Yog li ntawd, Gabriel's Phthalimide synthesis yog dab tsi?
Cov Gabriel synthesis yog tshuaj lom neeg cov tshuaj tiv thaiv uas hloov cov thawj alkyl halides rau hauv thawj amines. Yeej, cov tshuaj tiv thaiv siv cov poov tshuaj phthalimide . Cov tshuaj tiv thaiv muaj npe tom qab German chemist Siegmund Gabriel , leej twg thawj posited lub synthesis nrog kev pab ntawm nws tus khub, James Dornbush.
Cov tshuaj tiv thaiv thiab cov txheej txheem ntawm Gabriel Phthalimide yog dab tsi?
Cov Gabriel synthesis yog cov tshuaj tiv thaiv organic siv los hloov cov alkyl halide mus rau thawj amine siv phthalimide nrog lub hauv paus thiab ua raws li hydrazine. Cov tshuaj tiv thaiv pib nrog deprotonation ntawm phthalimide uas tom qab ntawd tawm tsam cov alkyl halide hauv SN2 zam muab N-alkylphthalimide nruab nrab.
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