Puas yog Imp ib qho nucleoside?

2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36

Inosinic acid los yog inosine monophosphate ( IMP ) yog a nucleoside monophosphate. Nws yog tsim los ntawm deamination ntawm adenosine monophosphate los ntawm AMP deaminase, thiab yog hydrolysed rau inosine. IMP yog ib qho nruab nrab ribonucleoside monophosphate hauv purine metabolism.

Ib yam li ntawd, koj tuaj yeem nug, IMP thiab GMP yog dab tsi?

Inosine 5'-monophosphate IMP ) yog ib ceg taw tes uas tuaj yeem ua rau AMP lossis GMP (Daim duab 22.6). Yog li, synthesis ntawm txhua nucleotide yog inhibited los ntawm cov khoom kawg ntawm txhua txoj kev ( GMP los yog AMP), thiab txhua ceg txoj kev sib txuas lus xav tau lub zog los ntawm lwm cov nucleoside triphosophate, ATP lossis GTP.

Ib yam li ntawd, nucleoside tsim li cas? Nucleosides feem ntau yog synthesized los ntawm kev sib txuas ntawm nucleophilic pyrimidine, purine, los yog lwm yam heterocycle yooj yim nrog ib tug derivative ntawm ribose los yog deoxyribose uas yog electrophilic ntawm cov anomeric carbon.

Ib yam li ntawd, Inosine ua khub nrog dab tsi?

Adenine hloov mus rau adenosine lossis inosine monophosphate (IMP), ob qho tib si, dhau los, hloov mus rau hauv inosine (I), uas ua khub nrog adenine (A), cytosine (C), thiab uracil (U). Inosine kuj yog ib qho nruab nrab hauv cov saw ntawm purine nucleotides cov tshuaj tiv thaiv uas xav tau rau cov leeg nqaij.

Yuav ua li cas yog hypoxanthine tsim?

Nws yog ib qho ntawm cov khoom ntawm kev ua ntawm xanthine oxidase ntawm xanthine. Txawm li cas los xij, ntau zaus hauv purine degradation, xanthine yog tsim los ntawm oxidation ntawm hypoxanthine los ntawm xanthine oxidoreductase. Hypoxanthine -guanine phosphoribosyltransferase converts hypoxanthine mus rau IMP hauv nucleotide khaws cia.