Video: Dab tsi yog qhov ua haujlwm ntawm Tfiih hauv qhov kev hloov pauv pib ua haujlwm?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
(NER) TSI yog ib tug general kev sau ntawv qhov tseem ceeb uas ua haujlwm los nrhiav RNA Pol II rau cov neeg txhawb nqa ntawm cov noob. Nws muaj nuj nqi raws li ib tug helicase uas unwinds DNA. Nws kuj tseem tshem tawm DNA tom qab qhov mob DNA tau lees paub los ntawm kev kho genome thoob ntiaj teb (GGR) txoj hauv kev lossis kev sau ntawv -coupled repair (TCR) pathway of NER.
Tsis tas li ntawd, lub transcription pib ua haujlwm ua haujlwm li cas?
Ua ke, lub kev sau ntawv yam thiab RNA polymerase tsim a complex hu ua transcription pib complex . Qhov no complex pib kev sau ntawv , thiab RNA polymerase pib mRNA synthesis los ntawm kev sib piv cov hauv paus ntsiab lus rau thawj DNA strand.
Tsis tas li ntawd, yuav ua li cas hloov cov ntsiab lus tswj cov noob caj noob ces? Transcription yam yog proteins uas tswj tus kev sau ntawv ntawm noob - uas yog, lawv luam tawm rau hauv RNA, ntawm txoj kev ua cov protein. Transcription yam pab kom ntseeg tau tias txoj cai noob yog qhia nyob rau hauv txoj cai hlwb ntawm lub cev, nyob rau lub sij hawm.
Ib yam li ntawd, tib neeg nug, dab tsi yog cov ntsiab lus ntawm kev pib ua haujlwm transcription?
Ib tug transcription-initiation complex muaj xws li ib tug RNA polymerase thiab ntau yam kev hloov pauv dav dav khi rau thaj tsam txhawb nqa. Ntau yam kev hloov pauv dav dav uas yuav tsum tau ua rau Pol II pib sau los ntawm feem ntau TATA-box txhawb nqa hauv vitro tau raug cais tawm thiab tus yam ntxwv.
Promotor clearance yog dab tsi?
Txhais: Txhua tus txheej txheem koom nrog kev hloov pauv los ntawm qhov pib mus rau elongation theem ntawm kev hloov pauv los ntawm DNA-dependent RNA polymerase, feem ntau suav nrog kev hloov pauv ntawm kev pib ua raws li kev sib haum xeeb mus rau elongation conformation.
Pom zoo:
Dab tsi yog qhov kev hloov pauv hloov pauv?
Kev hloov pauv, hauv molecular biology, yog hais txog kev hloov pauv hauv deoxyribonucleic acid (DNA), qhov twg ib qho (ob lub nplhaib) purine hloov pauv rau (ib lub nplhaib) pyrimidine, los yog vice versa
Dab tsi yog qhov txawv ntawm ib puag ncig kev hloov pauv thiab kev hloov pauv qub txeeg qub teg?
Qhov sib txawv ntawm cov yam ntxwv ntawm cov tib neeg ntawm tib hom yog hu ua variation. Qhov no yog inherited variation. Qee qhov kev hloov pauv yog qhov tshwm sim ntawm qhov sib txawv ntawm ib puag ncig, lossis ib tus neeg ua dab tsi. Qhov no yog hu ua environmental variation
Dab tsi yog kev saib xyuas ntawm kev ruaj ntseg sab hauv txawm tias muaj kev hloov pauv hauv ib puag ncig sab nraud?
Kev saib xyuas ntawm kev ruaj ntseg sab hauv txawm tias muaj kev hloov pauv hauv ib puag ncig sab nraud yog hu ua homeostasis
Dab tsi yog qhov kev hloov pauv ntawm cov khoom uas txav ntawm qhov chaw mus rau qhov chaw ntawm - 12 m?
Kev piav qhia: Qhov kev txav ntawm ib qho khoom txav ntawm qhov chaw mus rau qhov chaw ntawm − 12 m yog 12 meters. Qhov kev ncua deb ntawm lub hauv paus chiv keeb mus rau qhov siab tshaj plaws txoj hauj lwm yog hu ua displacement ntawm ib yam khoom. Qhov siab tshaj plaws kev hloov pauv ntawm cov khoom nyob rau hauv ib nthwv dej yog hu ua crest thiab qhov tsawg kawg nkaus hloov pauv yog hu ua trough
Peb qhov laj thawj tseem ceeb ntawm kev hloov pauv hloov pauv yog dab tsi?
Allele frequencies nyob rau hauv ib tug pej xeem yuav hloov vim plaub lub hauv paus zog ntawm evolution: Natural Selection, Genetic Drift, Mutations thiab Gene Flow. Kev hloov pauv yog qhov kawg ntawm cov alleles tshiab hauv cov noob caj noob ces. Ob ntawm cov txheej txheem tseem ceeb tshaj plaws ntawm kev hloov pauv hloov pauv yog: Natural Selection thiab Genetic Drift