Cov txheej txheem:

Cov tshuaj xoom xaj yog dab tsi?
Cov tshuaj xoom xaj yog dab tsi?

Video: Cov tshuaj xoom xaj yog dab tsi?

Video: Cov tshuaj xoom xaj yog dab tsi?
Video: Tshuaj theem vim li cas thiaj tau nqi ?/ Siv kho mob dab tsi?/paris polyphylla use for? 2024, Kaum ib hlis
Anonim

Xoom xaj : tus nqi tas li ntawm tshuaj raug tshem tawm hauv ib lub sijhawm. Piv txwv li, 10 mg ntawm a tshuaj tej zaum tshem tawm ib teev, qhov kev tshem tawm no tsis tu ncua thiab yog ywj siab ntawm tag nrho tshuaj concentration hauv plasma. Xoom xaj kinetics tsis tshua muaj tshem tawm mechanisms yog saturable.

Tom qab ntawd, qhov sib txawv ntawm cov tshuaj xoom xaj thiab cov tshuaj thawj zaug yog dab tsi?

Qhov tseem ceeb qhov sib txawv ntawm xoom thiab ua ntej - xaj kinetics yog lawv tshem tawm tus nqi piv rau tag nrho cov ntshav plasma concentration. Zero - xaj kinetics tau raug tshem tawm tas li tsis hais txog ntawm cov ntshav plasma concentration, tom qab ib theem kev tshem tawm raws li qhov system ua kom txaus.

Tsis tas li ntawd, cov tshuaj dab tsi ua raws li thawj qhov kev txiav txim kinetics? Tus nqi ntawm kev tshem tawm yog tas mus li thiab tsis nyob ntawm lossis txawv nrog kev noj tshuaj lossis ntshav plasma concentration ntawm cov tshuaj.

  • Phenytoin, Phenylbutazone.
  • Warfarin.
  • Heparin.
  • Ethanol.
  • Aspirin.
  • Theophylline, Tolbutamide.
  • Salicylates.

Ib yam li ntawd, tib neeg nug, yam tshuaj twg yog xoom xaj kinetics?

Daim ntawv teev cov tshuaj tom qab xoom-order kinetics

  • Phenytoin, Phenylbutazone.
  • Warfarin.
  • Heparin.
  • Ethanol.
  • Aspirin thiab lwm yam salicylates.
  • Theophylline, Tolbutamide.
  • Salicylates.

Puas yog phenytoin xoom xaj kinetics?

Phenytoin ua raws nonlinear (los yog xoom - xaj ) kinetics nyob rau hauv kev kho mob concentrations, vim hais tias tus nqi ntawm cov metabolism yog ze rau lub siab tshaj plaws muaj peev xwm ntawm cov enzymes koom tes. Hauv nonlinear kinetics , clearance thiab ib nrab-lub neej hloov pauv nrog plasma concentration.

Pom zoo: