Yuav ua li cas koj xam penetrance hauv noob caj noob ces?
Yuav ua li cas koj xam penetrance hauv noob caj noob ces?

Video: Yuav ua li cas koj xam penetrance hauv noob caj noob ces?

Video: Yuav ua li cas koj xam penetrance hauv noob caj noob ces?
Video: Tsis Paub Yuav Ua Li Cas - maim lis 2024, Kaum ib hlis
Anonim

Nco ntsoov tias nkag mus yog qhov tshwm sim ntawm tus kab mob muab ib qho genotype.

Txhua lub ntsiab lus no muaj lub ntsiab lus tshwj xeeb:

  1. P(D|A) = nkag mus .
  2. P(D) = lub hauv paus kev pheej hmoo (qhov kev pheej hmoo ntawm tus kab mob nyob rau hauv lub neej)
  3. P(A|D) = allele zaus nyob rau hauv rooj plaub.
  4. P(A) = allele zaus hauv cov pej xeem tswj.

Nyob rau hauv no txoj kev, koj yuav xam penetrance li cas?

Crude nkag mus Kev kwv yees tuaj yeem muab tau los ntawm kev faib cov naj npawb ntawm cov kab mob ( nkag mus ) cov tib neeg los ntawm tus lej ntawm cov neeg nqa khoom ua haujlwm ( nkag mus raws li txoj cai uas tsis yog- nkag mus , uas yog, cov tib neeg ib txwm muaj ntau tus xeeb leej xeeb ntxwv lossis cov tib neeg uas muaj kev cuam tshuam rau niam txiv thiab menyuam).

Tsis tas li ntawd, dab tsi yog penetrance thiab nthuav tawm hauv cov noob caj noob ces? Penetrance thiab kev nthuav qhia . Penetrance hais txog qhov tshwm sim ntawm cov noob caj noob ces los yog qhov zoo uas tau qhia. Qee qhov xwm txheej, txawm tias muaj qhov tseem ceeb ntawm allele, ib qho phenotype yuav tsis tshwm sim. Ib qho piv txwv ntawm qhov no yog polydactyly hauv tib neeg (ntiv tes ntxiv thiab / lossis ntiv taw).

Tom qab ntawd, ib tug kuj yuav nug, dab tsi penetrance txhais tau tias nyob rau hauv noob caj noob ces?

Penetrance hauv noob caj noob ces yog qhov kev faib ua feem ntawm cov tib neeg nqa ib qho txawv (los yog allele) ntawm ib tug noob (genotype) uas kuj qhia txog ib qho kev sib raug zoo (phenotype). Cov piv txwv zoo siv los qhia cov qib ntawm penetrance yog feem ntau heev nkag mus.

Dab tsi yog qhov txawv ntawm kev nthuav qhia thiab kev nkag mus?

Lub ntsiab qhov sib txawv ntawm kev nkag mus thiab kev nthuav qhia yog tias nkag mus yog ib qho kev ntsuas kom muaj nuj nqis, piav qhia txog qib ntawm kev qhia ntawm ib qho phenotype, uas sib haum mus rau qhov tseem ceeb genotype whereas kev nthuav qhia yog qhov twg ntawm qhov muab genotype qhia nyob rau theem phenotypic.

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