Video: Dab tsi ua rau somatic hypermutation?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Somatic hypermutation (los yog SHM) yog ib lub xovtooj ntawm tes uas lub cev tiv thaiv kab mob yoog rau cov khoom txawv teb chaws tshiab uas tawm tsam nws (xws li cov kab mob microbes), raws li pom thaum lub sij hawm hloov chav kawm. Somatic hypermutation Koom nrog cov txheej txheem kev hloov pauv uas cuam tshuam rau thaj chaw sib txawv ntawm cov noob ntawm immunoglobulin.
Tom qab ntawd, somatic hypermutation tshwm sim li cas?
Somatic hypermutation yog qhov tshwm sim uas muaj ntau zaus ntawm qhov kev hloov pauv tau tsim nyob rau hauv ib ntu 1-2-kb hauv thaj tsam sib txawv ntawm cov noob tshuaj immunoglobulin hauv kev teb rau qhov muaj cov tshuaj tiv thaiv.
Kuj Paub, puas yog somatic hypermutation tshwm sim hauv T hlwb? Somatic hypermutation ua tsis yog tshwm sim hauv T - cell receptor genes, yog li qhov sib txawv ntawm CDR1 thiab CDR2 cheeb tsam yog txwv rau cov germline V gene segments. Txhua qhov sib txawv hauv T - cell cov receptors yog generated thaum rearrangement thiab yog yog li ntawd tsom rau thaj tsam CDR3.
Tom qab ntawd, lub hom phiaj ntawm somatic hypermutation yog dab tsi?
Somatic hypermutation yog txheej txheem uas tso cai rau B hlwb hloov cov noob uas lawv siv los tsim cov tshuaj tiv thaiv. Qhov no ua rau cov B hlwb tsim cov tshuaj tiv thaiv zoo dua tuaj yeem khi rau cov kab mob, kab mob thiab lwm yam kab mob.
Qhov twg somatic recombination tshwm sim?
Somatic recombination tshwm sim ua ntej kev sib cuag antigen, thaum lub sij hawm B cell loj hlob nyob rau hauv cov pob txha pob txha.
Pom zoo:
Dab tsi ntawm pipette yog volumetric thiab nws siv rau dab tsi?
Lub volumetric pipette, noob pipette, lossis lub plab pipette tso cai rau kev ntsuas qhov tseeb (rau plaub qhov tseem ceeb) ntawm qhov ntim ntawm cov tshuaj. Volumetric pipettes feem ntau yog siv rau hauv analytical chemistry los ua cov kev daws teeb meem los ntawm lub hauv paus Tshuag thiab npaj cov kev daws teeb meem rau titration
S sawv rau dab tsi thiab dab tsi tshwm sim hauv theem no?
S theem sawv rau 'Synthesis'. Qhov no yog theem thaum DNA replication tshwm sim. The G2 stage stands for 'GAP 2'
Muaj pes tsawg chromosome khub nees muaj nyob rau hauv lawv cov somatic hlwb?
Cov dev muaj 39 khub ntawm chromosomes hauv lawv cov hlwb somatic. 3. Nees muaj 16 chromosomes hauv lawv cov hlwb haploid
Dab tsi yog qhov tseem ceeb tshaj plaws uas yuav tsum muaj rau cov kua dej ntws hauv cov kav dej Dab tsi lwm yam cuam tshuam rau cov dej ntws?
Thaum ib qho kev quab yuam sab nraud yog exerted rau ntawm cov kua uas muaj, qhov tshwm sim siab yog kis sib npaug thoob plaws hauv cov kua. Yog li txhawm rau kom dej ntws, dej xav tau qhov sib txawv siab. Cov kav dej kuj tuaj yeem cuam tshuam los ntawm cov kua dej, cov yeeb nkab loj, qhov kub thiab txias (cov kav dej khov), cov kua dej ntom ntom
Dab tsi yog qhov sib txawv tseem ceeb ntawm cov hlwb somatic thiab gametes?
Hauv tib neeg, cov hlwb somatic no muaj ob pawg ntawm chromosomes (ua rau lawv cov hlwb diploid). Gametes, ntawm qhov tod tes, koom tes ncaj qha rau hauv lub voj voog kev ua me nyuam thiab feem ntau yog cov hlwb haploid, txhais tau tias lawv tsuas muaj ib pawg chromosomes