Lub luag hauj lwm ntawm kev pib yam yog dab tsi?
Lub luag hauj lwm ntawm kev pib yam yog dab tsi?

Video: Lub luag hauj lwm ntawm kev pib yam yog dab tsi?

Video: Lub luag hauj lwm ntawm kev pib yam yog dab tsi?
Video: lub luag hauj lwm ua Vajtswv num los ntawm kev kho mob 2024, Kaum ib hlis
Anonim

Lo lus tseem ceeb - Initiation factor (KW-0396)

Protein uas plays ib qho tseem ceeb luag hauj lwm hauv kev pib kev txhais lus ntawm mRNA molecule rau hauv polypeptide. Pib yam tseem ceeb pab tsim cov complex ntawm mRNA thiab ribosome.

Ib yam li ntawd, lub luag haujlwm dab tsi pib ua hauv kev txhais lus?

Cov pib codon ntawm mRNA teeb tsa cov ntawv nyeem. Lub luag haujlwm ua li cas tus pib yam tseem ceeb ua si hauv protein synthesis ? kev ua haujlwm, uas yog qhov tsim nyog los daws cov txheej txheem thib ob. nyob nrog qhov kev pom zoo ib ntus hu ua Kozak sequence (5'-ACCAUGG-3').

Ib yam li ntawd, cov prokaryotes puas muaj qhov pib tshwm sim? Txhua tus kab mob yuav tsum tau siv peb pib yam tseem ceeb : IF1, thiab IF2, rau kev txhais lus. Qee qhov phyla xav tau IF3 ntxiv.

Ntawm no, qhov pib qhov tseem ceeb yog GTPase?

eIF5, eIF5A thiab eIF5B eIF5 yog a GTPase - activating protein, uas pab cov loj ribosomal subunit koom nrog cov me subunit.

Kev txhais lus pib yog dab tsi?

Thaum pib , lub me me ribosomal subunit khi rau qhov pib ntawm mRNA ib ntus. Tom qab ntawd ib qho kev hloov RNA (tRNA) molecule nqa cov amino acid methionine khi rau qhov hu ua pib codon ntawm mRNA ib ntus. Thaum lub sij hawm elongation theem, lub ribosome txuas ntxiv txhais txhua codon nyob rau hauv lem.

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