Qhov twg splicing tshwm sim nyob rau hauv lub cell?
Qhov twg splicing tshwm sim nyob rau hauv lub cell?

Video: Qhov twg splicing tshwm sim nyob rau hauv lub cell?

Video: Qhov twg splicing tshwm sim nyob rau hauv lub cell?
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Anonim

Rau nuclear-encoded noob, splicing tshwm sim nyob rau hauv lub nucleus nyob rau hauv lub sij hawm los yog tam sim ntawd tom qab transcription. Rau cov noob eukaryotic uas muaj introns, splicing feem ntau yuav tsum tau tsim kom muaj mRNA molecule uas tuaj yeem muab txhais ua cov protein.

Ib yam li ntawd, koj tuaj yeem nug, qhov twg yog qhov sib txuas tshwm sim hauv cov lus nug ntawm tes?

Nws tshwm sim hauv cell nucleus ua ntej RNA txhais.

Qhov thib ob, tus txheej txheem ntawm RNA splicing yog dab tsi? RNA sib txuas yog a txheej txheem uas tshem tawm cov kev cuam tshuam, uas tsis yog-coding sequences ntawm cov noob (introns) los ntawm pre-mRNA thiab koom nrog cov protein-coding sequences (exons) ua ke txhawm rau txhawm rau pab txhais cov mRNA rau hauv cov protein.

Qhov thib ob, puas splicing tshwm sim hauv cytoplasm?

Cov pa splicing ntawm introns los ntawm pre-mRNA los yog heteronuclear RNA (hnRNA) transcripts tshwm sim nyob rau hauv lub nucleus ntawm cov hlwb thiab koom nrog kev ua thiab kev sib koom ua ke ntawm ntau yam nucleic acid thiab protein cov ntsiab lus ntawm spliceosome. Kev ua haujlwm ntawm spliceosome hauv lub cytoplasm yog ib lub ntsiab lus tsis sib haum xeeb.

Yuav ua li cas lwm txoj kev splicing tshwm sim?

Splicing yog ib txoj kev uas tshwm sim nyob rau hauv lub nucleus ntawm cov hlwb uas tshem tawm cov sequences uas tsis tsim nyog los ua ib tug protein. Lwm txoj kev splicing tso cai rau lub cell ua ntau yam proteins los ntawm ib lub noob los ntawm kev muab cov exons ua ke nyob rau hauv ntau txoj kev.

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