Puas yog aneuploidy hloov pauv?
Puas yog aneuploidy hloov pauv?

Video: Puas yog aneuploidy hloov pauv?

Video: Puas yog aneuploidy hloov pauv?
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Anonim

Anuploidy : Ntxiv lossis tsis muaj chromosomes. Kev hloov pauv hauv cov khoom siv ntawm tes yog hu ua kev hloov pauv . Nyob rau hauv ib daim ntawv ntawm kev hloov pauv , cov hlwb yuav xaus nrog ib qho ntxiv lossis tsis muaj chromosome.

Raws li kev sib raug zoo, dab tsi kev hloov pauv ua rau aneuploidy?

Kev tsis sib haum xeeb hauv mitosis lossis meiosis yog qhov ua rau ntawm feem ntau aneuploids. Disjunction yog ib txwm sib cais ntawm homologous chromosomes los yog chromatids rau opposite ncej ntawm nuclear division. Nondisjunction yog qhov ua tsis tiav ntawm cov txheej txheem disjoining no, thiab ob chromosomes (los yog chromatids) mus rau ib tug ncej thiab tsis muaj rau lwm tus.

Ib sab saum toj no, Aneuploidies yog dab tsi? Anuploidy yog qhov muaj tus lej txawv txav ntawm cov chromosomes hauv ib lub xovtooj, piv txwv li tib neeg lub xovtooj ntawm tes muaj 45 lossis 47 chromosomes es tsis txhob muaj 46 li ib txwm. Nws tsis suav nrog qhov sib txawv ntawm ib lossis ntau dua chromosomes tiav. Ib lub cell uas muaj pes tsawg tus chromosome tiav yog hu ua euploid cell.

Raws li txoj cai, hom aneuploidy yog dab tsi?

Ib qho trisomy feem ntau yog trisomy 21 (Down syndrome). Lwm yam trisomies suav nrog trisomy 13 (Patau syndrome) thiab trisomy 18 (Edwards syndrome). Monosomy yog lwm qhov hom aneuploidy nyob rau hauv uas muaj ib tug uas ploj lawm chromosome. Ib qho monosomy yog Turner Syndrome, uas tus poj niam muaj qhov ploj lawm lossis puas X chromosome.

Dab tsi yog chromosomal mutation?

A kev hloov pauv koom nrog ib ntu ntev ntawm DNA. Cov no kev hloov pauv tuaj yeem koom nrog kev tshem tawm, ntxig, lossis hloov pauv ntawm ntu ntawm DNA. Qee qhov xwm txheej, cov seem deleted yuav txuas rau lwm yam chromosomes , disrupting ob lub chromosomes uas poob DNA thiab tus uas tau txais nws. Kuj hu ua a chromosomal kev kho dua tshiab.

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