T butoxide ua li cas rau cov tshuaj tiv thaiv?
T butoxide ua li cas rau cov tshuaj tiv thaiv?

Video: T butoxide ua li cas rau cov tshuaj tiv thaiv?

Video: T butoxide ua li cas rau cov tshuaj tiv thaiv?
Video: Tshuaj theem vim li cas thiaj tau nqi ?/ Siv kho mob dab tsi?/paris polyphylla use for? 2024, Kaum ib hlis
Anonim

tert - butoxide tuaj yeem siv los tsim cov "tsawg hloov" alkenes hauv kev tshem tawm cov tshuaj tiv thaiv (E2, tshwj xeeb). Feem ntau, kev tshem tawm cov tshuaj tiv thaiv haum rau "ntau hloov" alkene - uas yog, Zaitsev cov khoom.

Kuj paub yog, T BuOK puas muaj zog Nucleophile?

Exceptions: tert- BuOK yog ib heev muaj zog puag tab sis neeg pluag nucleophile , vim yog steric hindrance.

Tom qab ntawd, lo lus nug yog, vim li cas tert butoxide yog lub hauv paus muaj zog? Hauv (CH3) 3C-OH, conjugate acid ntawm lub tert - butoxide ion, qhov + kuv cuam tshuam rau cov cawv carbon yog peb zaug uas nyob rau hauv CH3-CH2-OH, conjugate acid ntawm ethoxide ion uas tsuas muaj ib pawg methyl. Thiab lub conjugate puag ntawm lub weaker acid yog ib txwm muaj zog dua tshaj li ntawm muaj zog dua kua qaub.

Tom qab ntawd, lo lus nug yog, puas yog T butoxide lub hauv paus muaj zog?

Potassium tert - butoxide yog cov tshuaj sib xyaw nrog cov mis K+(CH3)3CO. Cov khoom tsis muaj xim no yog ib lub hauv paus muaj zog (pKa ntawm conjugate acid nyob ib ncig ntawm 17), uas yog pab tau nyob rau hauv cov organic synthesis. Nws tshwm sim raws li tetrameric cubane-type pawg.

Puas yog tert butoxide yog Nucleophile zoo?

Kev piav qhia: Zoo Nucleophiles Ntawd Yog Lub Hauv Paus Tsis Muaj Zog (Qhov no yog txoj hauv kev nruj dua hais tias cov hauv paus tsis muaj zog tsis ua E2 cov tshuaj tiv thaiv). Hauv qhov sib piv, lub hauv paus loj hauv qab no ( tert - butoxide ion) yog lub hauv paus muaj zog tab sis cov neeg pluag nucleophile vim nws qhov kev cuam tshuam loj heev, yog li E2 cov tshuaj tiv thaiv muaj ntau dua li SN2.

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