Video: Dab tsi yog STRs hauv DNA?
2024 Tus sau: Miles Stephen | [email protected]. Kawg hloov kho: 2023-12-15 23:36
Ib luv tandem rov (STR) hauv DNA tshwm sim thaum tus qauv ntawm ob lossis ntau dua nucleotides rov ua dua thiab qhov rov ua ntu zus tau ncaj qha rau ib leeg. Los ntawm kev txheeb xyuas qhov rov ua dua ntawm ib ntu ntawm cov chaw tshwj xeeb hauv genome, nws muaj peev xwm tsim tau ib qho caj dab profile ntawm tus kheej.
Tsis tas li ntawd, vim li cas STRs tseem ceeb rau kev txheeb xyuas DNA?
STR alleles kuj muaj qhov hloov pauv qis dua, uas ua rau cov ntaub ntawv ruaj khov thiab kwv yees. Vim yog cov yam ntxwv no, STRs nrog lub zog siab dua ntawm kev ntxub ntxaug raug xaiv rau kev txheeb xyuas tib neeg hauv cov ntaub ntawv pov thawj tsis tu ncua. Nws yog siv los txheeb xyuas tus neeg raug tsim txom, tus neeg ua txhaum, cov neeg ploj, thiab lwm tus.
Tom qab, lo lus nug yog, STRs tau txais txiaj ntsig li cas? Alleles ntawm txawv STR loci yog tau qub txeeg qub teg zoo li lwm yam Mendelian caj ces cim. Diploid cov niam txiv txhua tus dhau ib qho ntawm lawv ob lub alleles rau lawv cov xeeb ntxwv raws li.
Hauv qhov no, muaj pes tsawg tus STRs?
Vim nyob ntawd 12 txawv alleles rau qhov no STR , nyob ntawd yog li ntawd 78 txawv tau genotypes, los yog khub ntawm alleles. Tshwj xeeb, nyob ntawd yog 12 homozygotes, hauv uas tib allele tau txais los ntawm txhua tus niam txiv, nrog rau 66 heterozygotes, hauv uas ob alleles txawv.
Dab tsi yog luv luv tandem rov ua dua STRs thiab lawv qhov tseem ceeb rau DNA ntaus ntawv yog dab tsi?
Nws yog ib qho txheej txheem uas tiv thaiv ntau tshaj ib qho STR hauv ib leeg DNA tsom xam. Nws yog tseem ceeb rau DNA profile vim tus ntau STRs tus kws tshawb fawb tuaj yeem ua tus cwj pwm, tus ntau lub caij nyoog uas lawv pib los ntawm tus tib neeg.
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